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[会议论文] 作者：Kaixin Wu,He Liu,Jiekai Chen,
来源：第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 年份：2015
Stedb1,known as a Histone H3 Lys9(H3K9)methyltransferase,plays an important role in maintaining embryonic stem(ES)cell identity.Paradoxically,its reported that Stedb1(Eset)can act as a barrier in plur...
[会议论文] 作者：Jing Liu,Zhiwei Zhou,Xuejie Yang,Jiekai Chen,
来源：第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 年份：2015
Histone demethylases have been linked to cell fate determination.However,little is known about how these enzymes integrate into the signaling machinery....
Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripoten
[会议论文] 作者：Yulin Chen,Weichen Zhou,Cheng Zhang,Jiucun Wang,Lin Guo,Jiekai Chen,Xiangjie Zhao,Duanqing Pei,Li Jin,
来源：The 7th Guangzhou International Conference on Stem Cell and 年份：2014
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Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripoten
[会议论文] 作者：Yulin Chen,Lin Guo,Jiekai Chen,Xiangjie Zhao,Weichen Zhou,Cheng Zhang,Jiucun Wang,Li Jin,Duanqing Pei,
来源：The 7th Guangzhou International Conference on Stem Cell and 年份：2014
Background:Induced pluripotent stem cells (iPSCs) derived from somatic cells have enormous potentials for clinical applications.Notably,it was recently reported that reprogramming from somatic cells t...
[期刊论文] 作者：Yuan Lv,Chen Bu,Jin Meng,Carl Ward,Giacomo Volpe,Jieyi Hu,Mengling Jiang,Lin Guo,Jiekai Chen,Miguel A.Esteban,
来源：基因组蛋白质组与生物信息学报（英文版） 年份：2021
Pluripotent stem cells (PSCs) can be expanded in vitro in different culture conditions, resulting in a spectrum of cell states with distinct properties. Understanding how PSCs transition from one state to another, ultimately leading to line......
Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids
[期刊论文] 作者：Zhang,Hao Sun,Lian Li,Xuejie Yang,Jiangping He,Shuqi Xiao,Jin Xiong,Ying Lin,Kun Wen,Hongwei Zhou,Jiekai Chen,
来源：蛋白质与细胞 年份：2021
The coronavirus disease 2019 (COVID-19) pandemic is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),which is spread primary via respiratory droplets and infects the lungs.Currently widely used cell ......
Pyrimidoindole derivative UM171 enhances derivation of hematopoietic progenitor cells from human plu
[会议论文] 作者：Zhao,Dan yang,Fangxiao Hu,Mengyun Zhang,Yang Geng,Yi Zheng,Hongling Wu,Xiaoli Chen,Guangjin Pan,Jiekai Chen,
来源：第九届广州国际干细胞与再生医学论坛暨第五届中国再生细胞生物学年会 年份：2016
In the field of hematopoietic regeneration,deriving induced hematopoietic stem cells(iHSCs)from pluripotent stem cells with engraftment potential is the central mission....
[会议论文] 作者：,Tongjie Wang,Chengxiang Xia,Xiaofei Liu,MinghuiMeng,Dan Yang,Yi Zheng,Juan Du,Xiangzhong Zhang,Jiekai Chen,
来源：第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 年份：2015
Generating engraftable hematopoietic stem cells(HSCs)from pluripotent stem cells(PSCs)is an ideal approach for obtaining induced HSCs for cell therapy.Howev...
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