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[会议论文] 作者：Peng R.Chen,
来源：第七届全国化学生物学学术会议 年份：2011
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[会议论文] 作者：Yi Yang,Peng R.Chen,
来源：第八届全国化学生物学学术会议 年份：2013
Epidermal growth factor (EGF) receptor is a tyrosine kinase which regulates cell growth and differentiation and is implicated in many human cancers.In vivo site-specific labeling of fluorescent or fun...
[会议论文] 作者：Xin Wang,Yanjun Liu,Peng R.Chen,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Bioorthogonal reaction pairs are playing more and more important role in chemical biology.Compared to traditional bioorthogonal coupling reaction,the biorth...
Site-specifically incorporated and decaged photo-affinity lysine to capture histone-effector interac
[会议论文] 作者：Lu Liu,Gong Zhang,Peng R.Chen,
来源：第十一届全国化学生物学学术会议 年份：2019
Post-translational modifications(PTMs) on lysine residues are essential histone marks for dynamic regulation of chromatin structure and gene transcription.Among them,unmodified lysine at certain site(...
[会议论文] 作者：Rongfeng Zhu,Yanqun Song,Haiping Liu,Peng R.Chen,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
The MarR type Zinc-specific transcriptional regulator ZitR contains two Zn(Ⅱ)-binding sites per dimeric subunit,with Site-1 being the primary Zn(Ⅱ)-sensin...
[会议论文] 作者：Rongfeng Zhu,Gong Zhang,Yu Han,Peng R.Chen,
来源：第十一届全国化学生物学学术会议 年份：2019
Formaldehyde(FA)has long been considered as a toxin and carcinogen due to its damaging effects to biological macromolecules,but its beneficial roles have been increasingly appreciated lately[1]....
[会议论文] 作者：Gong Zhang,Jie Li,Xinyuan Fan,Peng R.Chen,
来源：第十一届全国化学生物学学术会议 年份：2019
Kinases and GTPases,the major players in cell signaling pathways,control diverse biological processes in a precisely controlled manner....
[会议论文] 作者：Yicheng Weng,Wendong Chen,Ruijun Tian,Peng R.Chen,
来源：第十一届全国化学生物学学术会议 年份：2019
Tyrosine phosphorylation(p-Tyr)is a canonical form of cellular signaling transduction,deregulation of which can drive cancer germination....
[会议论文] 作者：Yicheng Weng,Yating Yao,Mingliang Ye,Peng R.Chen,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
BRAF is a serine/threonine protein kinase activating the MAP kinase/ERK-signaling pathway.Mutations of BRAF,over 90% V600E,can be detected in a wide range of human cancers.Better understanding of onco...
[会议论文] 作者：Jie Wang,Yuan Liu,Yanjun Liu,Chu Wang,Peng R.Chen,
来源：第十一届全国化学生物学学术会议 年份：2019
Precise perturbation of protein function with high selectivity and temporal resolution,especially in the gain-of-function manner,is crucial to dissect various dynamic biological processes.Although the...
Converting a heme-transfer complex to genetically encoded FRET sensors for imaging heme in living ce
[会议论文] 作者：Yanqun Song,Maiyun Yang,Yun Wu,Peng R.Chen,Chuan He,
来源：第八届全国化学生物学学术会议 年份：2013
Heme is a prosthetic group for many essential proteins involved in diverse biological processes, but excess heme can be highly toxic to cells.There is currently a lack of direct and quantitative metho...
[会议论文] 作者：Jun Liu,Jason Karpus,Seraphine V.Wegner,Peng R.Chen,Chuan He,
来源：第八届全国化学生物学学术会议 年份：2013
Copper represents one of the most important biological metal ions due to its role as a catalytic cofactor in a multitude of proteins.However, an excess of copper is highly toxic.Thus, copper is heavil...
DegP principally functions as a protease for the biogenesis of β-barrel outer membrane proteins in l
[会议论文] 作者：Xi Ge,Rui Wang,Jing Ma,Peng R.Chen,Xinmiao Fu,Zengyi Chang,
来源：第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 年份：2013
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DegP principally functions as a protease for the biogenesis of β-barrel outer membrane proteins in l
[会议论文] 作者：Xi Ge,Rui Wang,Jing Ma,Peng R.Chen,Xinmiao Fu,Zengyi Chang,
来源：第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 年份：2013
Protein quality control in cells involves molecular chaperones that promote folding and proteases that degrade misfolded proteins.DegP (also designated as HtrA)...
Profiling translating transcriptome with high spatial and temporal resolution via decaging proximity
[会议论文] 作者：Ruixuan Wang,Yanjun Liu,Ruixiang Wang,Huixin Luo,Peng R.Chen,Peng Zou,
来源：第十一届全国化学生物学学术会议 年份：2019
In eukaryotic cells,RNA can be translated in the specific areas.Local translation in the nervous system has been implicated in synapse plasticity,axon development and growth cone formation.Proximity-s...
[会议论文] 作者：Maiyun Yang,Yanqun Song,Meng Zhang,Dianmu Zhang,Ziyang Hao,Peng R.Chen,
来源：第八届全国化学生物学学术会议 年份：2013
Measuring the internal pH of living organisms below pH 5 is challenging.Whereas this extreme acidity will render fluorescent protein-based pH sensors denatured, the utilization of pH-sensitive fluores...
A highly efficient protein photo-cross-linking probe reveals a unique chaperone-chaperone protection
[会议论文] 作者：Meng Zhang,Xinwen Song,Zengyi Chang,Shixian Lin,Jun Liu,Peng R.Chen,Ye Fu,
来源：the 3rd Asia Pacific Protein Association Conference in ConJu 年份：2011
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,Light-induced protein translocation by genetically encoded unnatural amino acid in Caenorhabditis e
[期刊论文] 作者：Hao Chang,Mei Han,Wenming Huang,Guifeng Wei,Juanjuan Chen,Peng R.Chen,Runsheng Chen,
来源：蛋白质与细胞 年份：2013
Dear Editor,Living systems such as Caenorhabditis elegans are organized by interaction networks of biopolymer and small molecules.The molecular engineering of s...
A highly efficient protein photo-cross-linking probe reveals a unique chaperone-chaperone protection
[会议论文] 作者：Meng Zhang,Shixian Lin,Xinwen Song,Jun Liu,Ye Fu,Zengyi Chang,Peng R.Chen,
来源：the 3rd Asia Pacific Protein Association Conference in ConJu 年份：2011
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[会议论文] 作者：Maiyun Yang,Yanqun Song,Meng Zhang,Shixian Lin,Ziyang Hao,Yuan Liang,Dianmu Zhang,Peng R.Chen,
来源：The 9th Chinese Symposium on Calcium Signalling(第九届全国钙信号和细胞功 年份：2012
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