matrine相关论文
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Effect of Matrine on Human Ether à go-go Related Gene (HERG) Channels Expressed in Chinese Hamster O
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Fabrication of the supramolecular complexes of matrine by host-guest binding and electrostatic inter
Matrine (MAT) is widely used in the treatment of ulcerative colitis[1].However,it cannot reach an effective concentratio......
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Matrine inhibits the growth and induces apoptosis of osteosarcoma cells in vitro by inactivating the
Matrine,a natural product,has been demonstrated to be a promising chemotherapeutic drug for some cancers.Usingflowcytome......
Aim: We observed the effect of matrine on the expression of Nogo-A and NgR in experimental autoimmune encephalomyetic (E......
Aim: Chemotherapeutic drugs induced hyperalgesia and allodynia are common reasons of neuropathic pain, so effective ther......
Matrine ameliorates experimental autoimmune encephalomyelitis by regulating the differentiation of e
OBJECTIVE Experimental autoimmune encephalomyelitis (EAE), the classical animal model for multiple sclerosis (MS) is tri......
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Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-media
Matrine,a clinical drug in China,has been used to treat viral hepatitis,cardiac arrhythmia and skin inflammations.Matrin......
Matrine inhibits proliferation and induces apoptosis via BIDmediated mitochondrial pathway in esopha
Matrine,as a member of Sophora family,is an alkaloid found in plants,and produces plethora pharmacological effects,inclu......
Matrine-type alkaloids belong to quinolizidine analogues from Sophora flavescens Ait,Sophora subprostrata and Sophora al......
Matrine Inhibits the Proliferation, Invasion and Migration of Castration-Resistant Prostate Cancer C
BACKGROUND. Matrine is a naturally occurring alkaloid extracted from a Chinese herb Sophoraflavescens.Although it has de......
Aim of study:To observe the liver toxicity of matrine and to explore the related mechanisms,so as to provide the experim......
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Matrine suppresses lipopolysaccharide-induced fibrosis in human peritoneal mesothelial cells by inhi
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Compound Kushen injection induces immediate hypersensitivity reaction through promoting the producti
OBJECTIVE Compound Kushen injection(CKI)is a bis-herbal formulation extracted from Kushen(Radix Sophorae Flavescentis)an......
Anti-tumor and Phenotypic Regulation Effect of Matrine on Dendritic Cells through Regulating TLRs Pa
Objective:To investigate the effects of matrine on antigen presentation of dendritic cells (DCs),and to explore the phar......
Study on possible synergistic anticancer cachexia effects of the main active compounds of Radix Soph
Background:Cancer cachexia is a complex disease secondary to cancer,and no specific therapy for it has been found.The Ch......
采用密度泛函理论B3LYP方法计算了13个13位取代苦参碱衍生物的电子结构,研究了化合物结构与抑制人肝癌细胞HepG2抗癌活性的定量构......
采用高效液相色谱-紫外检测器建立了苦参药材指纹图谱,并对主要成分苦参碱和氧化苦参碱含量进行研究。苦参药材,用水冷浸提取后,直......
目的研究干旱胁迫下苦豆子子叶中赖氨酸脱羧酶(lysine decarboxylase,LDC)基因表达量与苦参碱(matrine,MA)和氧化苦参碱(oxymatrin......
Objective Searching the function that the Injection of the matrine hydrochloride prevents and cures acute chemical liver......
[Objectives] To provide theoretical foundation for protection and utilization of Sophora flavescens in Guizhou. [Methods......
Improvement of Identification Conditions for Thin Layer Chromatography of RADIX SOPHORAE FLAVESCENTI
[Objective] To improve the identification conditions for thin layer chromatography of RADIX SOPHORAE FLAVESCENTIS.[Metho......
目的:建立大鼠血浆中苦参碱浓度的LC-MS/MS测定法,研究苦参碱注射液、注射用苦参碱和苦参碱氯化钠注射液腹腔注射的体内药代动力学......
BACKGROUND: Studies on electrical signals of hippocampal brain slices in vivo have shown that matrine inhibits benzylpen......
Matrine promotes neural circuit remodeling to regulate motor function in a mouse model of chronic sp
In chronic phase of spinal cord injury, functional recovery is more untreatable compared with early intervention in acut......
Matrine inhibits proliferation of mouse skin fibroblasts induced by platelet-derived growth factor-B
To study the effect of matrine on proliferation of mouse skin fibroblasts induced by platelet-derived growth factor-BB (......
目的 评价中药苦参碱单独及联合阿苯达唑使用治疗小鼠继发性棘球蚴病的效果.方法 将感染棘球蚴的昆明小鼠分为4组:苦参碱组、阿苯......
The aim of this study was to select drugs for prevention and treatment of bovine papilloma in vitro, using bovine papill......
OBJECTIVE: To investigate the effect of Sophora flavescens alkaloid(SFA) in gel form on aerobic vaginitis(AV) and the po......
目的研究苦参素对实验性自身免疫性脑脊髓炎(EAE)大鼠钙蛋白酶(Calpain)和微管相关蛋白2(MAP-2)表达的影响。方法采用随机数字表法......
目的探讨苦参碱(Mat)诱导急性早幼粒白血病细胞株NB4细胞凋亡作用及机制。方法不同剂量M at(0.25、0.50、1.00 mg/m L)作用于NB4细......
目的用苦参提取苦参碱,对其纤维素酶提取法和传统提取法进行对比实验.方法纤维素酶提取法(简称酶提取法),即每克生药加入50U(0.25g......
目的:优选山豆根药材的提取工艺。方法:以提取物中苦参碱的含量为研究指标,采用高效液相色谱法测定其含量;比较水提醇沉法、60℃酸水浸......
目的通过比较对不同跨膜离子电流作用的效能、效价,探讨传统中药苦参碱抗心律失常作用弱于西药奎尼丁、维拉帕米的原因,确定苦参碱......
Effect of matrine on transforming growth factorβ1 and hepatocyte growth factor in rat liver fibrosis
Objective:To observe the preventive and control effect of matrine on transforming growth factor (TGF-β1) and hepatocyte......
目的 探讨苦参碱和X线对人肝癌HepG2细胞协同杀伤作用以及诱导细胞凋亡的机制.方法 采用MTT法检测细胞活力;ELISA试剂盒检测细胞凋......
Objective: To investigate the characteristics of CGI-100- knockdown K562 cells and the effect of CGI-100 RNA interferenc......
Objective:To investigate the effect of matrine against biofilm formation of Escherichia coli(E.coli)in the early stage.M......
Pathological cardiac fibrosis is a common feature in multiple cardiovascular diseases that contributes to the occurrence......
Study on possible synergistic anticancer cachexia effects of the main active compounds of RadixSopho
Background: Cancer cachexia is a complex disease secondary to cancer, and no specific therapy for it has been found. The......
AIM:To study the effect of matrine on activation of Kupffercell during cold ischemia and reperfusion injury in ratortho......
[Objectives] To establish a sensitive and simple thin layer chromatography method of matrine in Zhukuqin granule. [Metho......
本文采用冷压浸润法加工苦参,并与传统加工方法进行了质量对比,其实验结果证明,冷压浸润加工的苦参饮片质量明显优于传统方法加工......