pluripotency相关论文
GATA4, as a member of the GATA transcription factor family, plays a significant role in lineage specification and trans-......
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Plasticity of male germline stem cells and their applications in reproductive and regenerative medic
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Embryonic stem (ES) cells was isolated from blastocysts and grown as a cell line in culture.ES cells are pluripotent cel......
To better understand how Nanog functions in regulating self-renewal and maintaining pluripotency,we report in this study......
Jmjd1a and Jmjd2c are well-known epigenetic regulators that play significant role in stem cell identity through demethyl......
Oct4 heterodimerizes with Sox2 to direct a gene expression program establishing pluripotency.Oct4 also possess a lesser-......
Next generation unnatural monosaccharides reveal that FSRRB O-GlcNAcylation regulates pluripotency o
Unnatural monosaccharides such as azidosugars that can be metabolically incorporated into cellular glycans are currently......
Redox state mediates embryonic stem cell (ESC) differentiation and thus offers an important complementary approach to un......
Pluripotent stem cells (PSCs) can be expanded in vitro in different culture conditions, resulting in a spectrum of cell ......
Super-enhancers (SEs) comprise large clusters of enhancers,which are co-occupied by multiple lineage-specific and master......
Acidic pH transiently prevents the silencing of self-renewal and dampens microRNA function in embryo
Enhanced glycolysis is a distinct feature associated with numerous stem cells and cancer cells.However,little is known a......
Hepatocellular carcinoma(HCC)is a leading cause of cancer deaths.It is often detected at a stage when there are few ther......
Cancer stem cells(CSCs)are tumor cells that share functional characteristics with normal and embryonic stem cells.CSCs h......
Aurora kinase B and C differentially regulate mitosis and cell fate in mouse preimplantation embryos
Aurora kinases are evolutionarily conserved serine/threonine kinases and key regulators of mitosis.Aurora kinase B i......
Cardiomyocyte differentiation in vitro system from zebrafish embryos remains to be established.Here,we have determin......
在 2006， Shinya Yamanaka 在房间出版的一篇文章使干细胞研究社区大吃一惊。由执行系统的制动火箭，因素的病毒的 transduction 在胚......
LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripoten
LIN28A,an RNA-binding protein,plays an important role in porcine induced pluripotent stem cells(piPSCs).However,the mole......
Biological reactions require self-assembly of factors in the complex cellular milieu.Recent evidence indicates that intr......
Human pluripotent stem cells (hPSCs) are an important system to study early human development,model human diseases,and d......
Peach palm (Bactris gasipaes Kunth) has been micropropagated from pre-procambial cells that provide stem-like cell niche......
Acquisition of pluripotency in the chick embryo occurs during intrauterine embryonic development a u
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Fluorescent nanoswitch for monitoring specific pluripotency-related microRNAs of induced pluripotent
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective To clone, express, purify human Oct-4 and detect its subcellular localization.Methods Human Oct-4 cDNA was amp......
In vitro cultured embryonic stem (ES) cells are derived from the inner cell mass (ICM) of pre-implantation embryos, and ......
为研究Survivin对维持胚胎干细胞（ES细胞）多潜能性的影响,用1 μmol/L RA作为培养条件诱导ES细胞分化,通过Western blot与real-time ......
使用免疫荧光技术检测与增值、凋亡、多能性相关基因的表达水平。提高bFGF浓度可增强PCNA、Oct-4、Sox-2、Bax和Bcl-2的表达，同时使......
实验共设计了8对引物,即发育全能性的标志基因（OTC4）引物1对,管家基因（β-actin）引物1对,三胚层分别特异表达的基因引物各2对。每个胚......
神经干细胞可持续增殖、分化产生神经元、星型胶质细胞和少突胶质细胞.神经干细胞的这种特性为进行中枢神经退行性病变和损伤的治......
构建Stella基因真核表达质粒，转染小鼠胚胎干细胞（Embryonicstemcells，ESC）并初步探讨Stella对减数分裂起始相关基因（Stra／S）及胚胎干细胞......
Mammalian cell totipotency is a subject that has fascinated scientists for generations. A long lasting question whether ......
