3-Methyladenine相关论文
Rapamycin and 3-methyladenine regulate apoptosis and autophagy in bone-derived endothelial progenito
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Atorvastatin has been shown to reduce early brain edema and neuronal death after subarachnoid hemorrhage, but its mechan......
Expression of Beclinl in Osteosarcoma and the Effects of Down-regulation of Autophagy on the Chemoth
To explore the expression of Beclin1 in osteosarcoma and investigate the effects of down-regulation of autophagy on the ......
Rapamycin and 3-methyladenine regulate apoptosis and autophagy in bone-derived endothelial progenito
Background Mammalian target of rapamycin(mTOR)is involved in a caspase independent form of programmed cell death called ......
目的:探讨自噬对人肺腺癌细胞放疗敏感性的影响。方法采用透射电镜和荧光显微镜检测亲本人肺腺癌细胞SPC?A1和耐药细胞SPC?A1/DTX放......
目的 研究新生期大鼠反复惊厥后海马中Beclin-1急性期的表达及3-甲基腺嘌呤(3-MA)的干预作用.方法 生后6d的SD大鼠108只按照随机数......
目的 通过研究肠道病毒71型(Enterovirus 71,EV71)感染引起细胞的自噬及抑制自噬对病毒滴度的影响,为进一步明确EV71的致病机制提......
目的:探讨3-甲基腺嘌呤(3-MA)腹腔注射干预大鼠胃窦组织自噬的最佳药物剂量及用药时间。方法:将21只健康雄性SD大鼠随机分为七组:A......
目的:研究自噬抑制剂3-甲基腺苷(3-methyladenine,3-MA)对芹菜素诱导乳腺癌T47D细胞系自噬和凋亡的影响.方法:常规培养人乳腺癌T47D细......
目的:通过自噬抑制剂3-甲基腺嘌呤(3-MA)对阿霉素(ADM)诱导白血病K562细胞及K562/ADM细胞的细胞效应和自噬基因Beclinl、凋亡抑制基因Sur......
目的 探讨自噬在乳腺癌阿霉素耐药过程中发挥的作用。方法 采用大剂量阿霉素间歇诱导MCF-7细胞;应用MTT法检测阿霉素耐药细胞株MCF......
目的探讨自噬对脑缺血再灌注损伤的影响。方法 54只CD-1小鼠随机分为假手术对照组6只,缺血再灌注组24只,盐水对照组9只和3-MA组15......
期刊
目的探讨大鼠蛛网膜下腔出血(SAH)模型中,应用激动剂rapamycin(RAP)增强自噬后观察SAH后早期大鼠神经功能评分、脑水肿和血-脑屏障......