CHONDROCYTES相关论文
Nanomaterials including carbon nanotubes (CNTs) have attracted intense interest and shown great potential for biomedical......
Objective:Osteoarthritis(OA)is the most common joint degenerative disease affecting the joint structure,leading to loss ......
AComparisonofRabbitChondrocytesandMesenchymalStemCellsfromPeripheralBloodandBoneMarrow
Purposes:In this study,we evaluated whether mesenchymal stem cells(MSCs)from mobilized peripheral blood(PB)of New Zealan......
Aims:Osteoarthritis (OA) is the most common joint disorder and there is currently no effective drug treatment for the ea......
Background.The effects of gallic acid(GA)on arthritis are limited by its weak anti-oxidant effects and inferior bioactiv......
MicroRNA-92a-3p regulates the expression of cartilage-specific genes via directedly targeting histon
Objective:Increased activity of histone deacetylase 2(HDAC2)has been described in patients with osteoarthritis(OA)andcar......
Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocy
...
MicroRNAs(miRNA),small noncoding RNA molecules,are endogenous regulators of gene expression that have been implicated in......
Static Mechanical Stress Induces Apoptosis in Rat EndplateChondrocytes through MAPK and Mitochondria
Mechanical stress has detrimental effects on cartilaginous endplate chondrocytes due to apoptosis in vivo and in vitro.I......
Background Chondrocyte dedifferentiation is the one of the major factors that affect the clinic outcomes of autologous c......
Objective To evaluate the safety and efficacy of matrix-induced autologous chondrocytes implantation treatment(MACI,Genz......
OverexpressionofmicroRNA-1controlsthedevelopmentof osteoarthritisviatargetingFZD7ofWnt/β-
ackground Osteoarthritis(OA)isacommoncauseoffunctionaldeteriorationinolderadultsandisanimmenseburdenontheaging populatio......
The protective effect of resveratrol on chondrocytes in osteoarthritis and its underlying mechanisms
Objective:The study was designed to investigate the protective effect of resveratrol on chondrocytes in osteoarthritis a......
目的：种子细胞是软骨组织修复最大的难题之一,本研究试图对自体外周血细胞诱导分化为诱导全能干细胞(iPSCs)作为软骨修复的种子细胞......
Hydroxytyrosol inhibits the inflammatory response of osteoarthritis chondrocytes through SIRT6-media
Osteoarthritis (OA) is a common degenerative joint disease. Inflammation can exaggerate the catabolism and degeneration ......
Osteoarthritis(OA)is an age-related disease with poorly understood pathogenesis.Recent studies have demonstrated that mi......
Objective Inflammation is implicated to be involved in the pathogenesis of knee osteoarthritis(KOA).CXCL12,also known as......
RAGE/TLR4-regulated PPAR-γ signaling pathway mediates advanced glycation end products-induced inflam
Aim: Diabetes is a risk factor for osteoarthritis.Advanced glycation end products (AGEs) are important pathogenetic medi......
Universial Collagen Sponges for Enhanced Cartilage Regeneration: Native Collagen Versus Denatured Co
Nowadays, the responses of different cells to native collagen (Col) and denatured collagen (DCol) structure remain contr......
Histomorphometric study of the spinal growth plates in idiopathic scoliosis and congenital scoliosis
Background: Previous studies have suggested that the relative anterior spinal overgrowth may play an important role in t......
Histomorphometric study of the spinal growth plates in idiopathic scoliosis and congenital scoliosis
Background: Previous studies have suggested that the relative anterior spinal overgrowth may play an important role in t......
A Simple Strategy to Fabricate Concave Microwell Device for Chondrocytes Spheroids Formation and Phe
Chondrocytes are highly specialized cells of mesenchymal origin that are responsible for producing,sustaining and degrad......
H2O2 INDUCES APOPTOSIS OF RABBIT CHONDROCYTES VIA BOTH THE EXTRINSIC AND THE CASPASE-INDEPENDENT INT
Osteoarthritis (OA), one of the most common joint diseases with unknown etiology, is characterized by the progressive de......
...
组蛋白去乙酰化酶4(HDAC4)是Ⅱa类去乙酰化酶的一员，特异性分布于骨骼肌、心肌、神经系统、血管系统、骨、软骨及肝脏等组织中，不仅......
Chondrogenic potential of mesenchymal stem cells from horses using a magnetic 3D cell culture system
BACKGROUND Mesenchymal stem cells(MSCs)represent a promising therapy for the treatment of equine joint diseases,studied ......
Chondrogenesis of Human Adipose-Derived Stem Cells by In Vivo Co-graft with Auricular Chondrocytes f
Objective: To evaluate the efficiency of chondrogenesis of human adipose-derived stem cells (ADSCs) induced by auric......
目的探讨慢性肾衰竭（chronic renal failure，CRF）幼鼠胫骨生长板软骨细胞初级纤毛高表达加速软骨细胞分化的机制。方法选取雄性4周龄S......
目的 探讨转胰岛素样生长因子-Ⅰ(insulin like growth factor Ⅰ, IGF-Ⅰ)基因软骨细胞与交联透明质酸复合后在裸鼠体内形成组织......
为探讨黄腐酸能否直接刺激软骨细胞产生活性氧以及硒能否抑制由此产生的活性氧，采用二氯荧光互双酯作为软骨细胞产生过氧化氢的探讨......
肿瘤抑制蛋白p53是一种可以有效调节哺乳动物细胞生长的核磷酸化蛋白质。p53表达增加能够激活一系列细胞基因,通过抑制多个细胞周......
目的 探讨氟对体外培养人软骨细胞细胞活力和超微结构的影响.方法 采用细胞培养的方法,体外原代培养24～27周龄自然流产死亡胎儿的关......
目的观察氟对软骨细胞印度刺猬蛋白（Ihh）、甲状旁腺激素相关肽（PTHrp ）、跨膜蛋白（Smo ）表达和细胞增殖与凋亡的影响。方法原代培养乳鼠......
目的观察不同强度的机械牵张应力刺激对体外培养的小儿指骨骺板软骨细胞凋亡及软骨分化的影响，并探讨其相关机制。方法体外分离培养......
目的：本实验拟将分离纯化得到的滑膜间充质干细胞( synovial-derived mesenchymal stem cells，SMSCs )在体外培养条件下进行成软骨刺......
目的体外观察高强度周期性静水压对人膝关节软骨细胞形态和超微结构及其 II 型胶原分泌水平的影响。方法取正常成人膝关节软骨组织......
软骨生长板(CGP)主要由软骨细胞及细胞外基质(ECM)构成。软骨细胞的增殖、分化、肥大及ECM的形成,是骨骼发育、线性生长的关键。因......
目的探讨氧化损伤和硒对关节软骨细胞凋亡和硒蛋白基因表达的影响。方法采用细胞培养方法，培养人软骨细胞C28/I2。培养24 h后分别用......
T-2毒素是单端孢霉烯族真菌毒素中的有毒次级代谢产物，可导致软骨细胞的结构和功能改变、细胞变性和坏死，具有极强的软骨细胞毒性，对......
目的通过观察核转录因子κB（NF-κB）p65在大骨节病患者全血和软骨细胞（C28/I2）中的表达，分析NF-κB p65分子在软骨细胞凋亡中的作用，阐明......
目的研究T-2毒素对大鼠软骨细胞增殖和细胞周期的影响，为T-2毒素致软骨细胞损伤的分子机制研究提供新思路。方法提取新生Wistar大鼠......
目的观察胰岛素样生长因子-1受体（IGF-1R）在大骨节病（KBD）儿童和低硒条件下T-2毒素染毒大鼠软骨组织中的表达，以及IGF-1R抑制剂对人正常......
目的 观察人骺板软骨细胞与丝素支架在体外进行共培养的生物相容性.方法 将第一代人骺板软骨细胞与可降解的多孔丝素材料(支架)在......
背景：近期研究证实了固醇调节元件结合 蛋白2基因在骨关节炎发生过程中起重要作用，但其具体发病机制尚未完全清楚。目的：通过白细......
目的 研究透明质酸对重组大鼠白细胞介素-1β(rrIL-β)诱导体外软骨细胞基质金属蛋酶(MMP)及其抑制因子(TIMP) mRNA表达的影响,并......
目的 为骺板组织工程寻找生物相容性良好的支架材料.方法 将体外培养的第三代骺板软骨细胞与可降解多孔丝素材料复合.应用扫描电镜......
目的通过考查甘肃习用药材黄管秦艽栽培种和野生种中总裂环烯醚萜苷对白细胞介素-1β(IL-1β)诱导的大鼠软骨细胞的影响,探讨栽培......
目的:探讨大鼠软骨细胞与滑膜间充质干细胞以1:1比例接触式共培养,评价软骨细胞诱导干细胞在体外成软骨方向分化.方法:相同培养基......
目的 观察大鼠骨髓干细胞(BMSCs)诱导分化的软骨细胞,在具有三维孔隙结构的海绵状猪小肠粘膜下层(SIS)表面的生长情况,探讨SIS由薄......
目的 探讨低强度脉冲超声(low intensive pulsed ultrasound,LIPUS)干预后的同种异体软骨细胞-藻酸钙凝胶复合物修复兔膝关节软骨......
