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Superparamagnetic iron oxide-enhanced magnetic resonance imaging for focal hepatic lesions: Systemat
AIM: To evaluate the performance of superpara-magnetic iron oxide(SPIO)-enhanced magnetic resonance imaging(MRI) in the ......
Poor agreement between endoscopists and gastrointestinal pathologists for the interpretation of prob
AIM:To compare the interpretation of probe-based confocal laser endomicroscopy(p CLE)findings between endoscopists and g......
Hepatocarcinogenesis in human chronic liver diseases is a multi-step process in which hepatic precancerous lesions progr......
Objective To detect the expression level of growth differentiation factor 11(GDF11)in patients with myelodysplastic synd......
Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell
AIM:The transcription factor EGR-1(early growth responsegene-1)plays an important role in cell growth,differentiation a......
AIM:To systematically study the expression of carbonicanhydrase (CA) isozymes Ⅸ and Ⅻ in gastric tumors.METHODS:We an......
Role of inducible nitric oxide synthase expression in aberrant crypt foci-adenoma-carcinoma sequence
AIM:To investigate the expression of inducible nitric oxidesynthase (iNOS) in aberrant crypt foci (ACF) -adenoma-carcin......
Expression of a plant-associated human cancer antigen in normal,premalignant and malignant esophagea
AIM:To study the relationship between the expressionprofiles of a plant-associated human cancer antigen andcarcinogenes......
In situ detection of TGF betas, TGF beta receptor II mRNA and telomerase activity in rat cholangioca
AIM Initial report on the in situexamination of the mRNAexpression of transforming growth factor betas(TGFβS),TGFβ typ......
Expression of transforming growth factor-α and hepatitis B surface antigen in human hepatocellular c
AIM:To evaluate the expression of transforming growthfactor-alpha (TGF-α) and hepatitis B surface antigen (HBsAg)in hu......
BACKGROUND: Some reports have confirmed that occur-rence and development of tumor are related with lots of on-cogene, an......
AIM To investigate the relationship between theexpression of p16 gene and the gastric carcinogenesis,depth of invasion ......
The most frequent cause of pseudomembranous colitis is Clostridium difficile(C.difficile) infection.This type of colitis......
Long term omeprazole therapy for reflux esophagitis:follow-up in serum gastrin levels,EC cell hyperp
AIM To evaluate the long-term safety ofomeprazole in patients of gastroesophagealreflux disease resistant to treatment ......
Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyi-N-nitro-N-nitrosog
INTRODUCTIONGastric epithelial dysplasia(GED)hypothetically isa straight-forward concept:dysplastic epitheliumreplacing......
Objective To investigate the role of the burden of abnormal hematopoietic clone in the development of myelodysplastic sy......
The abnormal expression of retinoic acid receptor-β,p53 and Ki67 protein,n normal,premalignant and m
AIM:Esophageal cancer remains a significant healthproblem worldwide.It is important to investigate alterationsin expres......
Combined treatment of vitamin K_2 and angiotensin-converting enzyme inhibitor ameliorates hepatic dy
Although it is well known that the hepatocellular carcinoma (HCC) is an ominous complication in patients with liver cirr......
Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute v......
Prevention and therapy of squamous cell carcinoma of the rodent esophagus using freeze-dried black r
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Endoscopy is a keystone in the management of patients with inflammatory bowel disease(IBD).It is the fundamental diagnos......
Despite significant therapeutic progress in recent years,inflammatory bowel disease(IBD),which includes Crohn’s disease......
BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by multicause, obvious multistage and multifocal processes o......
Pi(Spleen)-Deficiency Syndrome in Tumor Microenvironment Is the Pivotal Pathogenesis of Colorectal C
Cancer immunoediting consists of three sequential phases: elimination, equilibrium, and escape. For colorectal adenoma-c......
In 2010, a panel of Chinese pathologists reported the first expert consensus for the pathological diagnosis of primary l......
Expression of p16 gene and Rb protein in gastric carcinoma and their clinicopathological significanc
AIM: To analyze the correlation between the protein expression of p16 and Rb genes in gastric carcinoma (GC), to investi......
Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-re
AIM: Expression of heat shock proteins (HSPs) is frequently up-regulated in hepatocellular carcinoma (HCC), which evolve......
Expression of cyclooxygenase-2 is associated with p53 accumulation in premalignant and malignant gal
AIM: To examine the relationship between cyclooxygenase-2 (COX-2) overexpression and p53 accumulation in gallbladder car......
AIM: To study the role of an insertion/deletion polymorphism in the pepsinogen C (PGC) gene, an effective marker for ter......
Helicobacter pylori eradication to prevent gastric cancer: underlying molecular and cellular mechani
Numerous cellular and molecular events have been described in development of gastric cancer. In this article, we overvie......
Well to moderately differentiated HCC manifesting hyperattenuation on both CT during arteriography a
We present a rare case of well-to moderately-differentiated hepatocellular carcinoma (HCC) in a 71-year-old woman with h......
Multistep hepatocarcinogenesis from a dysplastic nodule to well-differentiated hepatocellular carcin
We describe a rare case of the transformation of a dysplastic nodule into well-differentiated hepato- cellular carcinoma......
Mucinous cyst exhibiting severe dysplasia in gastric heterotopic pancreas associated withe gastroint
Heterotopic pancreatic tissue within the stomach is rare and dysplasia within heterotopic pancreatic tissue is very rare......
With the support by the National Natural Science Foundation of China and the Chinese Academy of Sciences,the research gr......
AIM: To determine the role of Sonic hedgehog (Shh) pathway in colorectal adenocarcinomas through analysis of the express......
Ultrasonography(US) findings are inevitably based on pathological features.Knowledge of the pathological features of hep......
Hepatocarcinogenesis is a process attributed to progressive genomic changes that alter the hepatocellular phenotype prod......
AIM: To investigate whether defi ciency of expressionof cytochrome c oxidase I (CcOI) in colonic crypts is associated wi......
Attention has recently been focused on biliary papillary tumors as the novel disease entity intraductal papillary neopla......
Association of p53/p21 expression with cigarette smoking and prognosis in esophageal squamous cell c
factors,such as cigarette smoking,in esophageal squamous cell carcinoma(ESCC)in northeastern Iran,a region with a high i......
High-grade dysplasia(HGD) in Barrett’s esophagus(BE) is the critical step before invasive esophageal adenocarcinoma.Alt......
AIM:To reveal the manner of hepatocellular carcinoma (HCC) development in patients with nonalcoholic steatohepatitis(NAS......
Diagnostic efficacy of gadoxetic acid-enhanced MRI for hepatocellular carcinoma and dysplastic nodul
AIM:To evaluate the relationship between the signal intensity of hepatobiliary phase images on gadoxetic acid-enhanced m......
AIM: To investigate miR-200 family expression in Barrett’s epithelium, gastric and duodenal epithelia, and esophageal a......
AIM:To characterize aberrant crypt focus (ACF) in adjoining mucosa in sporadic colorectal carcinoma and to evaluate frag......
When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia,it is difficult for......
Neuroendocrine carcinoma (NEC) of the extrahepatic bile duct is rare, and only 22 cases have been reported. Only two of ......
AIM:To evaluate the histopathological findings of type C liver disease to determine risk factors for development of hepa......
Differentiation between dysplastic nodule and early-stage hepatocellular carcinoma: The utility of c
AIM:To elucidate the variety of ways early-stage hepatocellular carcinoma(HCC)can appear on magnetic resonance(MR)imagin......