G-protein-coupled相关论文
目的 探讨INSL3和LGR8在单侧隐睾症患儿睾丸鞘膜及引带中的表达和临床意义.方法 采用RT-PCR技术检测INSL3和LGR8在42例单侧隐睾儿......
目的探索生物纳米盘(Nanodisc)在G蛋白偶联受体(GPCR)体外功能和药物筛选研究方面的应用。方法将重组表达获得的5-羟色胺2B受体(5-......
目的 探讨血管紧张素Ⅱ(AngⅡ)对肺微血管内皮细胞APJ mRNA和Apelin mRNA表达的影响.方法 培养并鉴定24 h新生SD大鼠肺微血管内皮......
目的 采用大鼠胚胎H9C2心肌细胞研究心肌缺氧再灌注损伤后,新型雌激素受体-G蛋白偶联受体30(G protein-coupled receptor 30,GPER)......
目的探讨富含亮氨酸的G蛋白偶联受体5(LGR5)和乙醛脱氢酶1A1(ALDH1A1)的表达在非小细胞肺癌(NSCLC)进展和预后中的作用,为NSCLC的诊......
目的:观察apoE敲除小鼠主动脉组织尾加压素Ⅱ受体-GPR14表达的变化,以探讨UⅡ及其受体系统在动脉粥样硬化发病中的作用.方法:取不......
Desensitization of G-protein-coupled receptors induces vascular hypocontractility in response to nor
BACKGROUND: The increased β-arrestin-2 and its combination with G-protein-coupled receptors (GPCRs) lead to GPCRs desen......
AIM:To generate a Gpr128 gene knockout mouse model and to investigate its phenotypes and the biological function of the ......
MicroRNA-760 acts as a tumor suppressor in gastric cancer development via inhibiting G-protein-coupl
BACKGROUND Gastric cancer(GC)has become a serious threat to people's health.Accumulative evidence reveals that dysre......
目的探讨冠心病患者血清中抗G-蛋白偶联受体自身抗体的分布特征.方法选择冠心病患者131例,正常健康体检者100名,采用链酶亲和素-酶......
目的构建G蛋白偶联受体40(Gprotein coupled receptor 40,GPR40)shRNA表达载体质粒,获得干扰质粒稳定转染的小鼠βTC6细胞系。方法将......
Chronic inflammatory pain resulting from arthritis,nerve injury and tumor growth is a serious public health issue.One of......
为了提高G蛋白偶联受体(G-protein-coupled receptors,GPCR)与药物相互作用预测的精度.该文提出一种基于多视角特征组合与随机森林的GP......
G蛋白偶联受体30(G protein-coupled receptor 30,GPR30)是上世纪90年代发现的一种膜相关雌激素受体(estrogen receptor,ER),其作用模......
Coronary heart disease(CHD) continues to be the greatest mortality risk factor in the developed world. Estrogens are rec......
GRK4 A486V variant contributes to ischemic injury by repressing autophagy after myocardial infarctio
Background G-protein–coupled receptor kinases (GRKs) play important roles in cardiac hypertrophy and heart failure. The......
目的研究胆囊结石患者胆囊黏膜G蛋白偶联胆汁酸受体1(GPBAR1)表达与致石胆汁形成的关系。方法收集34例胆囊结石病和15例无胆石对照患......
Relationship of GPRC6A and PKCzeta expression levels in prostate cancer lesions with cell proliferat
Objective: To study the relationship of GPRC6A and PKCzeta expression levels in prostate cancer lesions with cell prolif......
Blood vessels either form de novo through the process of vasculogenesis or through angiogenesis that involves the sprout......