GALECTIN相关论文
Background: Hco-gal-m and-f were two isoforms of galectin cloned from male and female Haemonchus contortus,respectively,......
Sec途径(分泌途径,Secretion pathway)是蛋白质转运的主要途径。其中,SecA ATPase是蛋白质转运途径中的“动力泵”,它通过ATP的水......
Background: Hco-gal-m and -f were two isoforms of galectin cloned from male and female Haemonchus contortus,respectively......
Galectin Hco-gal-m from Haemonchuscontortus modulates goat monocytesand T cell function in different
Monocytes and T cells are two major subpopulations of peripheral blood mononuclear cells(PBMC)and play an essential role......
Symbiotic microbes play a crucial role in regulating parasite–host interactions;however,the role of bacterial associate......
Transmembrane protein 147(TMEM147)another partner protein of Haemonchus contortus galectin on the go
Recombinant galectins of male and female Haemonchus contortus(rHco-gal-m/f)have been recognized as significant regul......
胰腺实性-假乳头状肿瘤是主要发病于年轻女性的非常少见的肿瘤。尽管具有低度恶性潜能,但10%~15%的病例具有转移播散可能导致死亡......
随着分子生物学、分子免疫学、细胞信号转导理论等领域的进展,有关晚期糖基化产物(advanced glycation end products,AGE)及其受体......
胎盘蛋白13(placental protein 13,PP13)是从人类足月胎盘中克隆的一种蛋白,根据序列分析、整合及计算机模拟,揭示了其保守的序列......
Objective: Keshan disease (KD) is a fatal endemic dilated cardiomyopathy with unclear etiology and pathogenesis, and a h......
目的研究不同心功能等级心力衰竭患者血半乳凝集素3(galectin-3)表达水平及其与心脏结构和功能的关系。方法选取96例慢性心力衰竭......
循环半乳凝素3(circulating galectin-3,Gal-3)浓度与心力衰竭、心房颤动、慢性肾脏病及死亡率相关。近来研究结果表明,Gal-3还是......
近期许多研究表明 ,galectin存在于许多组织中 ,与肿瘤细胞的转移、浸润、生长和黏附有关。galectin在某些恶性肿瘤中高表达 ,如前......
甲状腺结节是临床上常见病 ,发病率高 ,在人群中约占5 % ,甲状腺肿瘤在内分泌肿瘤中是最常见的肿瘤 ,其中恶性肿瘤约 5～ 1 0 %。对......
Objective:Thisstudyaimsto screenthedifferentiallyexpressedgenesof glioblastomausingmicroarraytech-nique.Methods:Specimen......
Protein/carbohydrate interactions through specific protein families termed lectin control essential biological processes......
Galectins are a family of endogenousβglycan-binding proteins that play an important role in the modulation of inflammat......
Past,present and future of preserving and restoring function in the visual system: removing galectin
Great advances in retinal ganglion cells survival(RGCs),optic nerve preservation and regeneration have been made in the ......
半乳糖凝集素(galectin)是一个广泛分布于微生物、植物和动物(包括寄生虫)中的蛋白家族。随着后基因组学和功能蛋白质组学研究的深......
捻转血矛线虫主要寄生于反刍动物尤其是绵羊的胃内,可引起宿主的贫血、抵抗力下降甚至死亡。周期性服用抗虫药和粪检是当今的控制......
目的:探讨白藜芦醇对人宫颈癌SiHa细胞增殖和凋亡的影响及galectin-3在其中的作用。方法:以体外培养的人宫颈癌SiHa细胞为研究对象......
目的:研究galectin-3在雌性小鼠生殖系统的表达情况,利用小鼠生殖道感染模型研究galectin-3在女性生殖道感染过程中的可能作用。方......
目的探讨galectin-3对骨髓间充质干细胞(MSCs)来源的内皮细胞增殖的影响。方法密度梯度离心法分离纯化SD大鼠骨髓MSCs,取第3代,加......
凝集素属于β-半乳糖苷结合蛋白家族,广泛存在于昆虫的体内,对其免疫调控起重要作用,研究埃及伊蚊(Aedes aegypti)中的凝集素具有......
目的克隆、表达广州管圆线虫(Angiostrongylus cantonensis)半乳糖凝集素-1(galectin-1)基因并分析其凝集反应。方法用Swiss Model......
胰腺实性假乳头状肿瘤(SPT)是一种好发于年轻女性的罕见肿瘤。尽管其具有低度恶性潜能,10%~15%有转移播散的侵袭性行为,可能导致死......
Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells vi
AIM: To investigate the role of pancreatic stellate cells (PSCs) and galectin-3 (GAL-3) in the proliferation and infiltr......
AIM: To discuss the expression of glactin-3 in liver metastasis of colon cancer and its inhibition by modi- fied citrus ......
ROLE OF PANCREATIC STELLATE CELLS AND GALECTIN-3 ON PROLIFERATION AND INFILTRATION OF HUMAN PANCREAT
Objective To investigate the role of pancreatic stellate cells (PSCs) and galectin-3 (GAL-3) on the proliferation and in......
目的探讨galectin-3在小鼠结肠癌肝转移中的表达及MCP对其抑制的作用。方法75只Balb/c小鼠随机分为阴性对照组,阳性对照组,低浓度M......
β-半乳糖苷结合蛋白广泛存在于多种生物组织中,属于动物凝集素家族,通过调节免疫和炎症反应,参与瘤细胞的恶性转化,肿瘤细胞的生......
目的观察galectin-1对LoVo细胞生长的影响。方法构建galectin-1真核表达载体转染LoVo细胞,观察LoVo细胞生长情况。用免疫细胞化学......
Increased concentrations of free circulating galectin-3 are commonly seen in the blood circulation of patients with many......
Gliomas and melanomas are associated with dismal prognosis because of their marked intrinsic resistance to proapoptotic ......
目的探讨galectin-3和CD105在结直肠癌组织中的表达及其与临床病理特征的关系。方法应用微波-EliVisionTM免疫组织化学染色技术检......
目的:评价慢病毒介导的RNA干扰技术对小鼠胰腺星状细胞(mPSC)中半乳糖凝集素-1(galectin-1)基因的沉默效应,并观察其对mPSC增殖的......
目的研究甲状腺乳头状癌中D2-40,CK19,galectin-3,VEGF和EGFR的表达及其临床意义。方法应用免疫组化法检测38例甲状腺乳头状癌和12......
半乳凝素-3(galectin-3,Gal-3)、促血管生成素-2(Ang-2)、肝肠钙黏着蛋白(LI-cadherin)是近年来受到普遍关注的与肿瘤相关的物质。......
Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor
AIM: To evaluate the expression of galectin-1 and vascular endothelial growth factor (VEGF) in gastric cancer and invest......
传统的结/直肠癌化疗药物,作用选择性较低,副反应明显,疗效欠佳,患者病死率居高不下。寻找新型治疗药物,十分必要。在结/直肠癌发......
Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammati
Hepatocellular carcinoma(HCC)represents a global health problem.Infections with hepatitis B or C virus,non-alcoholic ste......
目的研究半乳凝素-9(galectin-9)对胶质瘤细胞系U251增殖和迁移能力的影响,并探讨其作用机制。方法利用实时定量PCR方法检测胶质瘤......
本文通过对荣华二采区10...
目的应用RNA干扰技术抑制人舌癌细胞株Tca8113和SCC-4中Rho A基因的表达,探讨Rho A基因表达下调对舌癌细胞侵袭的影响。方法登录Ge......
在过去的一个世纪,许多肿瘤指标被发现,其中包括Galectin-3,它在肿瘤的发生与发展过程中所起的作用正日益受到重视。Galectin-3是......
Gastrointestinal cancer is a group of tumors that affect multiple sites of the digestive system, including the stomach, ......
