Methylatio相关论文
Metabolic disease results from a complex interaction of many factors,including genetic,physiological,behavioral and envi......
The Effect of Chinese Tea on Occurrence of Esophageal Tumor Induced by N-Nitrosomethylbenzylamine in
Five groups of rats (40 rats per group) were given five different varieties of Chinese tea (1 g/50 ml) and another two ......
Total synthesis of N-methylsansalvamide A was accomplished in solution phase by a convergent approach. An N-Boc-tri-deps......
AIM:To evaluate the accuracy of methylation of genes in stool samples for diagnosing colorectal tumours.METHODS:Electron......
Colorectal cancer(CRC) is the third leading cause of cancer death worldwide, which is consequence of multistep tumorigen......
The insulin-like growth factor(IGF) signaling path-way is an important pathway in the process of hepa-tocarcinogenesis,a......
DNA 甲基化是一种十分重要的表观遗传修饰,与转座元件沉默、基因组印记以及X染色体失活等多种生物学过程相关。胚胎特异性转录因子......
目的探讨浸润性乳腺癌及相应癌旁乳腺组织中分泌型卷曲相关蛋白1(the secreted frizzled-relat-ed protein 1,SFRP1)基因的表达及其......
Alteration of oncogenic IGF-Ⅱ gene methylation status associates with hepatocyte malignant transform
Background:Oncogenic insulin-like growth factor-Ⅱ(IGF-Ⅱ)is overexpressed in hepatocellular carcinoma(HCC).The present ......
为了探究饲料不同脂肪水平对黄颡鱼卵巢脂肪代谢潜在的影响,本研究设计了活体与离体两个实验。活体实验中,分别投喂3组不同脂肪水......
目的探讨颈静脉球体瘤中凋亡相关基因诱捕受体1(decoyreceptor 1,DcR1),诱捕受体2(DcR2),死亡受体4(deathreceptor 4,DR4),死亡受体5(DR5)......
目的探讨结肠癌组织中,Syk、P16基因启动子甲基化与术后复发转移的关系。方法采用甲基化特异性PCR检测结肠癌组织及癌旁正常结肠组......
以氢氧化钠水溶液为缩合剂、邻苯二酚和硫酸二甲酯为原料,在氮气保护下,采用两步升温法合成藜芦醚。考察了水和甲醇溶剂对氢氧化钠反......
目的:研究WIF-1(WntinhibitoP/factor-1)mRNA在乳腺癌组织中的表达及其启动子区域甲基化情况,进-步探讨WIF-1基因甲基化与乳腺癌临床病......
在现行检测标准条件下,2-萘胺和1-萘胺的气相色谱保留时间相近,且质谱图完全相同,所以,1-萘胺会对2-萘胺的检测造成干扰.将氨基完......
目的:探讨甲基化转移酶抑制剂5-氮杂-2-脱氧胞苷(5-aza-CdR)抑制脾源性酪氨酸激酶(Syk)基因启动子的甲基化后对髓母细胞瘤Daoy细胞侵袭......
目的分析大肠癌(colorectal cancer,CRC)组织中unc5c基因启动子区域甲基化的改变状况及其临床意义。方法运用甲基化特异性PCR技术,检......
目的探讨5-氮杂-2'-脱氧胞苷(5-Aza-CdR)对胃癌细胞系SGC7901的p27kip1基因异常甲基化及表达的影响。方法选择不同浓度的5-Aza-CdR处......