N-methyl-D-aspartate相关论文
目的:评价N-甲基-D-天冬氨酸受体(NMDA受体)在七氟烷麻醉致老龄小鼠海马神经元程序性坏死中的作用。方法:清洁级健康雄性C57BL/6小......
Tongluo Huatan capsule(通络化痰胶囊)improves cognitive func-tion by regulating the endocytosis of N-methyl
OBJECTIVE:To explore the neuroprotective mecha-nisms of Tongluo Huatan capsule (THC) in a rat model of vascular dementia......
Ionotropic glutamate receptors in medial prefrontal cortex and dorsal hippocampus are involved in di
Objective The medial prefrontal cortex (mPFC) and dorsal hippocampus (DHC) play significant roles in stimulant-induced n......
The effects of ANEPⅢ, a new recombinant neurotoxic peptide, on behavior and brain neuronal activity in animal studies h......
Corticosterone induced D-serine release deficit play an important role in long-term potentiation imp
OBJECTIVE Previous studies showed that over activation of NMDA receptors may be a crucial cause of long-term potentiatio......
目的分析抗髓鞘少突胶质细胞糖蛋白（MOG）抗体合并抗N-甲基-D-天冬氨酸受体（NMDAR）抗体双阳性患者的临床特点，提高临床医生对此类疾病的......
目的 探讨东莨菪碱与氯胺酮对幼鼠海马乙酰胆碱酯酶(AchE)和NMDA受体2B亚基mR-NA(NR2BmRNA)的相互影响.方法 1月龄筛选合格SD大鼠4......
N-methyl-D-aspartate receptor expression in the spinal dorsal horn of a rat model of formalin-induce
Clinical and animal experiments have proved that intrathecal injection of butorphanol has an analgesic effect. However, ......
N-methyl-D-aspartate receptor subunit 1 regulates neurogenesis in the hippocampal dentate gyrus of s
N-methyl-D-aspartate receptor hypofunction is the basis of pathophysiology in schizophrenia. Blocking the N-methyl-D-asp......
突触后致密物( PSD)是位于中枢神经系统突触后膜的特殊结构，它是由一系列细胞骨架蛋白与受体、激酶等传递突触信号相关分子结合形成......
AIM:To investigate the effects of ketamine anesthesia on the motility alterations and tissue injury caused by ischemia/r......
目的 建立豚鼠形觉剥夺性近视动物模型,玻璃体腔内注射不同浓度的N-甲基-D-天冬氨酸受体1(NMDAR1)反义寡核苷酸(ASON),观察NMDAR1 ......
目的 研究N-甲基-D-天冬氨酸(NMDA)受体亚型NR2B是否参与雌激素增加应激大鼠内脏敏感性的作用.方法 健康成年雌性Wistar大鼠,剪除......
目的 探讨鞘内注射艾芬地尔对骨癌痛小鼠脊髓N-甲基-D-天冬氨酸(NMDA)受体2B亚基(NR2B)mRNA表达的影响.方法 雄性C3H/HeJ小鼠140只......
Although exogenous D-serine has been applied as a neural regulatory intervention in many studies, the role played by D-s......
N-甲基-D-天冬氨酸(NMDA)受体是一类对Ca2+高度通透性配体门控离子通道。NMDA受体在脑发育突触可塑性、学习记忆方面都起到重要作......
,Cysteinyl leukotriene receptor 1 is involved in /N-methyl-D-aspartate-mediated neuronal injury in m
Aim: To determine whether cysteinyl leukotriene receptor 1 (CysLT1 receptor) is involved in N-methyl-D-aspartate (NMDA)-......
,Effects of intracerebroventricular NMDA and non-NMDA receptor agonists or antagonists on general an
The efiects of intracerebroventricular(icv)agonists and antagonists of N-methyl-D-aspartate(NMDA)and alpha-amino-3-hydro......
,Neuroprotective effect of deferoxamine on N-methyl-D-aspartate-induced excitotoxicity in RGC-5 cell
Many N-methyI-D-aspartate (NMDA) receptor antagonists have been used to treat neurodegenerative diseases induced by glut......
目的检测慢性胰腺炎(CP)大鼠大脑前扣带回(ACC)的N-甲基-D-天冬氨酸受体亚基NR2A和NR2B基因表达水平，探讨其在CP疼痛形成中的作用。......
Dual effects of 3, 4-methylenedioxymethamphetamine (ecstasy) on survival and apoptosis of primary hi
BACKGROUND: 3, 4-methylenedioxymethamphetamine (MDMA, also known as ecstasy) has been shown to exhibit neurotoxic effect......
目的通过观察黄芪总苷和N-甲基-D-天冬氨酸(NMDA)受体拮抗剂对宫内窘迫诱发的缺血缺氧强应激后新生鼠Tau蛋白超磷酸化的影响，探讨两......
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目的通过检测首次发病抑郁症患者外周血中miRNA-219和钙调蛋白激酶Ⅱγ亚基mRNA（γCaMKⅡ mRNA）表达水平，分析探讨其与抑郁症之间的关......
目的研究重复高＋Gz暴露后，大鼠三叉神经脊束核尾侧亚核(spinal trigeminal nucleus caudalis, SpVc)内P物质(substance P)与N-甲基-D......
目的:观察电针对吗啡戒断大鼠空间学习记忆能力及前额叶皮质NR2B(N-甲基-D-天门冬氨酸受体NR2B亚单位)表达的影响,探讨电针治疗药......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Dual effects of 3, 4-methylenedioxymethamphetamine (ecstasy) on survival and apoptosis of primary hi
BACKGROUND: 3, 4-methylenedioxymethamphetamine (MDMA, also known as "ecstasy") has been shown to exhibit neurotoxic effe......
脑卒中具有极高的致死率和致残率,在当今老龄化社会中其危害性日益突出.N-甲基-D-天冬氨酸受体(NMDAR)是一类配体门控离子型谷氨酸......
N-methyl-D-aspartate receptor expression in the spinal dorsal horn of a rat model of formalin-induce
Clinical and animal experiments have proved that intrathecal injection of butorphanol has an analgesic effect. However, ......
本研究利用受体自显影方法探讨了孤啡肽(nociceptin/orphanin FQ)在外周炎症和痛觉过敏中的调制作用.将完全弗氏佐剂(CFA)注射到大......
In the central nervous system, Asiaticoside has been shown to attenuate in vitro neuronal damage caused by exposure to ......
目的 研究N-甲基-D-天冬氨酸受体1(NMDA-R1)在SD大鼠—过性肠道感染旋毛虫后形成的内脏高敏感中的作用.方法 40只SD大鼠均分为健康......
目的 评价脊髓NMDA受体在大鼠糖尿病神经病理性痛中的作用.方法 雌性Wistar大鼠,月龄3月,体重180～220 g,腹腔注射链脲菌素65 mg/kg......
目的 评价N-甲基-D天冬氨酸受体2B亚基(NR2B)基因重组腺病毒(rAd5/NR2B)对神经病理性痛大鼠认知功能的影响.方法 雌性SD大鼠40只,......
目的检测肠道炎症后内脏高敏感幼鼠中枢前扣带回皮质（ ACC ）区域NMDA受体亚基NR2A、NR2B的表达变化。方法以芥子油结肠灌注建立炎症......
目的 研究亚慢性染铝对断乳大鼠学习记忆和海马细胞内Ca2+及磷脂酶C(phospholipase C,PLC)、N-甲基-D-天冬氨酸受体α(NMDARα)表......
目的 探讨抗N-甲基-M-天冬氨酸(NMDA)受体脑炎的临床特点、诊断及治疗.方法报道1例伴卵巢畸胎瘤的抗NMDA受体脑炎患者的临床表现及......
目的 研究孕期酒精暴露对子代大鼠学习记忆及海马N-甲基-D-天冬氨酸(NMDA)受体2B亚基(NR2B)表达的影响.方法 按照随机数字表法,将......
目的 评价蛛网膜下腔注射Ro25-6981对大鼠局灶性脑缺血再灌注损伤的影响.方法 清洁级健康雄性SD大鼠60只,体重280～320 g,采用随机数......
目的 探讨抗N-甲基-D-天冬氨酸受体(N-methyl- D-aspartate receptor,NMDAR)脑炎的临床特征与抗NMDAR抗体在诊断该病中的意义.方法......
总结了22例抗N-甲基-D-天冬氨酸受体脑炎患儿的护理.护理要点包括:精神行为异常的护理、惊厥护理、中枢性通气不足护理、自主神经......
AIM:To investigate the effects of ketamine anesthesia on the motility alterations and tissue injury caused by ischemia/r......
目的：探讨非典型抗精神病药奥氮平对N-甲基-D-天门冬氨酸（NMDA）受体拮抗剂MK-801处理大鼠自发活动和额叶微小RNA（miRNA）-219表达的影响......
在过去的十几年中,抗脑抗体被发现与各种自身免疫疾病相关[1]。根据其结合的抗原,可将其分为结合神经元或非神经元的抗体,结合细胞......
大量研究表明激活中枢神经系统N-甲基-D-天门冬氨酸（N-methyl—D—aspartate,NMDA）受体在神经病理性疼痛的产生和维持中起重要作用，NM......
目的观察丙泊酚对癫痫持续状态（SE）大鼠皮层NMDA受体亚型（2A，2B）表达的影响。方法60只SD大鼠随机分为空白对照组（BLK组）、SE组、丙泊酚50m......
采用一次性被动回避性条件反射方法,给小鼠icvN-甲基-D-门冬氨酸(NMDA)10,1和0.1 ng。结果表明:对正常小鼠,在跳台法中NMDA 10 ng......
