NONALCOHOLIC相关论文
Objective: To investigate the effect of fibroblast growth factor-21(FGF-21)on triglyceride(TG)of nonalcoholic fatty live......
Desulfovibrio vulgaris,a potent acetic acid-producing bacterium,increased by Astragalus polysacchari
OBJECTIVE Although the underlying mechanism is largely unknown,gut dysbiosis has emerged as a central initiator of obesi......
Naringenin prevented nonalcoholic steatohepatitis fibrosis via regulating MAPK/FoxO3a pathway and pr
OBJECTIVE The pathological characteristics of nonalcoholic steatohepatitis(NASH)include liver steatosis,inflammation,and......
Nonalcoholic fatty liver disease(NAFLD)is the most common cause of liver disease worldwide,and its prevalence increases ......
Intestinal microbiota participates in nonalcoholic fatty liver disease progression by affecting inte
Nonalcoholic fatty liver disease(NAFLD)is a chronic liver disease with a pathogenesis that has not been fully elucidated......
Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in re......
Impact of continuous positive airway pressure therapy for nonalcoholic fatty liver disease in patien
BACKGROUND Obstructive sleep apnea(OSA)has been suggested as an independent risk factor for nonalcoholic fatty liver dis......
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a major chronic liver disorder worldwide,and there is no establishe......
With the increasing incidence of obesity and metabolic syndrome worldwide,concomitant nonalcoholic fatty liver disease(N......
Nonalcoholic fatty liver disease(NAFLD)is becoming a frequent liver disease,especially in patients with metabolic syndro......
目的 探讨菲酒精性脂肪肝(NAFLD)患者发生2型糖尿病(T2DM)的危险因素及与颈动脉硬化的关系.方法 选择51例NAFLD合并初诊T2DM患者(N......
Prevalence of HFE mutations and relation to serum iron status in patients with chronic hepatitis C a
AIM: To assess the prevalence of the two mutations, C282Y and H63D of HFE gene, in healthy subjects, patients with chron......
The rapid global spread of coronavirus disease 2019(COVID-19)infection has become a major health issue with higher morbi......
目的 研究老年男性非酒精性脂肪肝(NAFLD)患者腹部脂肪面积及血清脂联素和瘦素水平的变化.方法 选择238名年龄≥60岁的老年男性,应......
目的 通过观察非酒精性脂肪性肝纤维化形成过程中肝组织内骨桥蛋白(OPN)的变化规律,探讨OPN在非酒精性脂肪性肝纤维化形成过程中的......
目的 研究非酒精性脂肪性肝病(NAFLD)患者肝组织因醇凋节元件结合蛋白-1c(SREBP-1c)的表达变化,探讨其在NAFLD中的作用. 方法对临......
抵抗素通过减弱胰岛素信号级联反应中多个环节的作用减弱胰岛素的作用,导致胰岛素抵抗(IR),另外,抵抗素可以通过激活核因子-KB(NF-......
目的 研究门冬氨酸-鸟氨酸颗粒剂治疗非酒精性脂肪性肝炎的临床疗效和安全性.方法 用多中心开放性多剂量平行对照的临床试验设计选......
一、Hedgehog通路概况Hedgehog (Hh)信号通路最初是在果蝇中发现的,该通路非常保守,在胚胎发育过程中,其决定着许多关键细胞的命运......
非酒精性脂肪性肝病(NAFLD)正在成为我国一个新的公共健康问题[1].PNPLA3 (patatin-like phospholipase domain-containing protei......
目的 探讨血清高敏C反应蛋白(hsCRP)水平对2型糖尿病患者发生非酒精性脂肪肝(NAFLD)风险的预测价值. 方法 此研究为前瞻性队列研究......
目的 研究非酒精性脂肪性肝病(NAFLD)家兔肠上皮细胞紧密连接、肠道大肠杆菌、肠黏膜Toll样受体4(TLR4)与肿瘤坏死因子α(TNF α)......
目的 探讨利拉鲁肽改善肝脏脂肪沉积的潜在分子机制.方法 8周龄雄性C57BL/6J小鼠标准饲料喂养作为野生对照组(WT组,n=10);ApoE KO......
目的 比较并探讨2型糖尿病(T2DM)及其合并非酒精性脂肪性肝病(NAFLD)的代谢相关危险因素. 方法 选取2012年10月至2013年7月住院的T......
随着糖尿病和肥胖在世界范围内流行,与之密切相关的非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)正日益成为公共......
目的 探讨载脂蛋白(APO) C3基因启动子区两位点多态性T-455C、C-482T与非酒精性脂肪性肝病(NAFLD)遗传易感性的相关性.方法 对287......
目的探讨C-反应蛋白（CRP）对新发非酒精性脂肪肝（NAFLD）的预测价值。方法采用前瞻性队列研究，以参加2006年7月至2007年10月健康体检的101......
肝细胞肝癌（HCC）是恶性程度很高、预后极差、严重危害人类健康的重大疾病。慢性病毒性肝炎（乙型、丙型肝炎）-肝硬化-肝癌的发病模式已......
跨膜6超家族成员2（TM6SF2）是近些年来被发现的一个基因，该基因定位于第19号染色体上(19p12)，编码由351个氨基酸构成的蛋白。目前有很多......
随着肥胖的流行和生活方式的改变，全球非酒精性脂肪性肝病(NAFLD）已成为第一大肝病，在接下来的10多年中其患病率仍将进一步增高。NAFL......
目的：探讨上海大学生非酒精性脂肪肝病(nonalcoholic rattyliver disease，NAFLD)与载脂蛋白E(ApoE)基因多态性相互关系。
方法：采......
目的 通过研究慢性丙型肝炎合并非酒精性脂肪肝患者外周血单个核细胞(PBMC)中肿瘤坏死因子(TNF-α)的表达,初步探讨慢性丙型肝炎患......
目的 通过高脂饮食诱导幼龄大鼠建立非酒精性脂肪性肝病(NAFLD)模型.方法 3周龄刚离乳SD大鼠30只,雌雄各半,随机分为正常(N)组、20......
目的 探讨内质网应激在非酒精性脂肪性肝纤维化形成中的作用及饮食控制对脂肪性肝纤维化恢复的影响.方法 蛋氨酸-胆碱缺乏饮食 (MC......
Nonalcoholic fatty liver disease and cardiovascular concerns:The time for hepatologist and cardiolog
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most commonchronic liver cell damage worldwide. It is strong......
With the growing prevalence of obesity and diabetes in the United States and across the world,a rise in the overall inci......
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)affects more than one-quarter of the global population.Due to the lack......
BACKGROUND Many studies have investigated the progression of nonalcoholic fatty liver disease(NAFLD)and its predisposing......
Cannabis use history is associated with increased prevalence of ascites among patients with nonalcoh
BACKGROUND Recent studies have revealed the endocannabinoid system as a potential therapeutic target in the management o......
Adult human liver slice cultures:Modelling of liver fibrosis and evaluation of new anti-fibrotic dru
BACKGROUND Liver fibrosis can result in end-stage liver failure and death.AIM To examine human liver fibrogenesis and an......
目的:探讨脂肪相关基因(fat mass and obesity associated gene,FTO)及其抑制剂大黄酸(rhein)在非酒精性脂肪肝病(non-alcoholic f......
This study presents a simple and robust three-dimensional human hepatic tissue model to emulate steatotic and fibrotic c......
目的观察祛痰活血方通过调控SOCS1抑制TLR4/NF-κB信号通路改善非酒精性脂肪性肝炎小鼠肝损伤的作用。方法30只SPF级雄性C57BL/6J......
Nonalcoholic fatty liver disease(NAFLD)is a broad-spectrum disease,ranging from simple hepatic steatosis to nonalcoholic......
目的：观察理气化痰祛瘀中药对高脂饮食诱导的非酒精性脂肪性肝炎（NASH）大鼠血浆前列环素、血栓素的影响，探讨其防治NASH的作用机理。方......
Non-alcoholic fatty liver disease (NAFLD) is currently not a component of the diagnostic criteria for metabolic syndrome......
目的：观察二甲双胍及吡格列酮对非酒精性脂肪性肝病（NAFLD）的治疗效果。方法：136例NAFLD患者，随机分为对照组、二甲双胍治疗组、毗格列......
目的 观察普罗布考对大鼠非酒精性脂肪性肝病（NAFLD）的预防作用．并探讨其可能作用机理。方法 24只雄性sD大鼠随机分3组：正常对照组、NA......
目的 研究非酒精性脂肪性肝病（nonalcoholic fatty liver disease,NAFLD）患者肝穿刺组织中脂肪量与肥胖相关基因（fat mass and obesit......
