Oligodeoxynucleotides相关论文
Oligodeoxynucleotides (oligos hereafter) are short (20~50 nt) and single stand DNA molecules which are widely used in gen......
Antiviral effect of antisense oligodeoxynucleotides complementary to hepatitis B virus X gene in vit
Objective To investigate the antiviral effect of antisense phosphorothioate oligodeoxynucleotides (ASODNs) complementary t......
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Reversing drug resistance in the ovarian carcinoma cell line SKOV3/mdr1 in vitro by antisense oligod
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目的 寻找抗HBV最佳反义寡核苷酸区段。方法 合成4种互补于HBV不同区段的反义硫代寡核酸(asON),加入HBV基因转染的肝癌细胞模型HepG22.2.15,以ELSA法测定HBsAg、HBeAg含量。结......
,Structure-efficacy relationships of immunostimulatory activity of CpG-containing oligodeoxynucleoti
Aim: To study the relationship between primary structures of oligodeoxynucleo-tides (ODN) containing unmethylated deoxyc......
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Effect of anti-sense oligodeoxynucleotides homeobox B2 on the proliferation and expression of primar
Objective: To explore the effect of homeobox B2 (HOXB2) antisense oligodeoxynucleotides (asodn) on the proliferation a......
目的探讨脂质体-硫代磷酸化修饰的C-erbB2反义脱氧寡核苷酸(C-erbB2 antisense phosphorothioated oligodeoxynucleotides, C-erbB......
Effect of anti-sense oligodeoxynucleotides homeobox B2 on the proliferation and expression of primar
Objective: To explore the effect of homeobox B2 (HOXB2) antisense oligodeoxynucleotides (asodn) on the proliferation an......
目的:观察Bcl-2反义硫代磷酸寡脱氧核苷酸(ASODN)对人胆管癌QBC939细胞的作用及对Bcl-2蛋白表达的影响.方法:脂质体LipofectamineT......
目的:研究反义硫代磷酸寡核苷酸(asODN)抑制人神经母细胞瘤细胞系S100A4基因表达的作用.方法:将S100A4反义寡核苷酸通过脂质体转染......
目的探讨核转录子κB(NF-κB)decoy寡核苷酸(ODNs)对结肠癌SW480细胞Toll样受体4(TLR)4表达的影响。方法体外培养SW480细胞,LPS(10μg/L)刺......
观察增殖细胞核抗原(PCNA)反义寡核苷酸对人肝癌细胞株体外增殖的影响及生物学特性的改变.方法 MTT法、集落形成试验观察PCNA反义......
目的研究寡核苷酸(ODN)mt01对人牙周膜细胞向成骨细胞分化的影响,为临床药剂的开发奠定实验基础。方法采用人离体牙牙周膜细胞作为研......
目的探讨β1整合素反义寡核苷酸(ASODN)对裸鼠人胰腺癌移植瘤生长和基因表达的影响.方法建立裸鼠人胰腺癌皮下移植瘤模型,随机分为......
目的探讨核转录因子κB(NF—κB)“诱骗(decoy)”寡核苷酸(ODNs)对结肠癌SW480细胞IL-8表达的影响。方法体外培养SW480细胞,LPS(10μg/L)刺......
为了探讨局部应用反义C-myc寡核苷酸对血管吻合口狭窄的抑制作用,将30只新西兰大白兔颈外静脉间置于同侧颈总动脉后随机分成对照组......
目的探讨bcl-2-反义寡核苷酸(bcl-2-AODN)对卵巢癌顺铂(DDP)耐药细胞耐药性的逆转作用.方法以卵巢癌顺铂耐药细胞株A2780/DDP为模......
目的研究Bcl-2反义核酸(ASODN)对人胆管癌QBC939细胞增殖的影响.方法将Bcl-2ASODN与QBC939细胞共同孵育,采用台盼蓝拒染实验检测细......
目的观察寡聚脱氧核苷酸(ODN)对THP-1细胞NF-κB核转位及细胞核内结合活性的抑制作用。方法用脂质体将寡聚脱氧核苷酸转入细胞后,以细......
目的探讨核转录因子-κB(NF-κB)"诱骗(decoy)"寡核苷酸(ODNs)对脂多糖(LPS)诱导的结肠癌SW480细胞IL-1β表达的影响。方法体外培养SW480细胞......
目的:应用反义寡核苷酸技术,对培养的人肾小球系膜细胞(glomerular mesan gial cells, GMC)进行内皮素-1(endothelin,ET-1)基因表......