aconitine相关论文
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Aim: Aconitine (AC) is a toxic alkaloid from some Chinese medicinal herbals with origin of genus Aconitum, which have be......
Aim Aconitine and its structurallyrelated diterpenoid alkaloids have been shown to interact differentially with neuronal......
Na/K Pump Current Inhibition and INa-TTX Stimulation Involved in Aaconitine-induced Arrhythmia in Gu
Aconitine has potential cardio-and neurotoxicity and can produce various arrhythmias, so its application in the clinic i......
Aconitine is a major bioactive diterpenoid alkaloid with high content derived from herbal aconitum plants.Emerging evide......
Aconitine, a famous active and toxic alkaloid, has no impact on the activities of CYP1A2, CYP2D6, CY
Aconitine (AC) is a famous major diterpenoid alkaloid present in the roots of Aconitum species (Ranunculaceae family).Ac......
Comparative analysis of stability and hydrolysis of Aconitine by liquid chromatography-mass spectrom
Aconitine is a typical diterpenoid alkaloid of medicinal interest, which can be found in many plants such as Aconitum ca......
Effects of the compatibility of Radix Aconiti Laterlis and Radix Glycyrrhizae on the Pharmacokinetic
A simple and sensitive high performance liquid chromatographic method coupled with electrospray ionization mass spectrom......
目的:考察人参及其主要成分人参皂苷Rb1,Rb2,Re,Rg1和附子及其主要成分乌头碱配伍后对CYP2J3,CYP4A3和CYP4F11 mRNA表达的影响。方......
Matrix solid-phase dispersion(MSPD) was developed for the extraction of four alkaloids, including aconitine, mesaconitin......
[Objective]To establish methods to determine the content of Aconitine,Yunaconitine,Crassicauline and Vilmorrianine in Ac......
Rapid construction of the unique BCD ring system of tricyclo[6.2.1.0] undecane in the C_(19)-diterpe
A model study leading to the preparation of the unique tricyclo [6.2.1.0] undecane BCD ring systems of aconitine is desc......
AIM: The present study was designed to test a hypothesis that nonfatal ventricular arrhythmia such as ventricularprematu......
Four new diterpenoid alkaloids,nagaconitines A-D(1-4),were isolated from the roots of Aconitum nagarum var.heterotrichum......
目的：完善八味黄连跌打水的质量标准，控制药品质量。方法采用TLC法对八味黄连跌打水中乌头碱限量进行检查。结果确定了最佳提取方法......
目的:对铁棒锤和工布乌头进行对比,以证明两者是否存在差异,是否需要区别用药。方法:进行两种药材的显微特征、薄层色谱的比较,采......
1例46岁男性患者误服生草乌、川乌粉约5 g后3 h出现意识障碍、全身抽搐；心电图检查示心室扑动，心率110次/min。立即电除颤，静脉推注胺......
目的建立同时测定血液、肝组织中新乌头碱(mesaconitine)、乌头碱(aconitine)、次乌头碱(hypaconitine)含量的HPLC分析方法。方法......
INTRODUCTION. 7-hydroxy-8-methoxy-4(1H) quinolone(Q), C_(10)H_9NO_3, is a new compound isolated from the Chinese soft c......
AIM: To investigate the anticancer activity of a chinese medical mixture, WRCP (warming and relieving Cold Phlegm), on h......
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
从内蒙古赤峰产的北草乌中共分得五种结晶性的生物碱,并证明其中四种为已知物,即去氧乌头碱(deoxyaconitine),次乌头碱(hypaconiti......
伏毛铁棒锤Aconitum flavum Hand-Mazz系我国西北地区民间常用草药,块根为活血为瘀,祛风湿,止痛止血药,其总生物碱部分临床用于多......
本文采用薄层层析-光密度法分离和测定草乌及其炮制品中乌头碱(aconitine)、中乌头碱(mesaconitine)和下乌头碱(hypaconitine)三种......
从拟玉龙乌头Aconitumpseudostapfianum根中分得10个二萜生物碱，其结构通过波谱和化学方法分别鉴定为14－benzoyl－8－O－methyl－aconine（Ⅰ），ac......
首次从优毛铁棒锤Aconilumflavum地上部分（花、茎、叶）中分离出4个生物碱结晶。经鉴定晶Ⅰ为脱氧乌头碱（deoxyaconitine），晶Ⅱ为3-乙酰......
Aim:The present work was designed to investigate the relationship betweenhemodynamic parameters and the susceptibility ......
Based on the advance in research by domestic and foreign scholars,the paper mainly introduces the advances of Aconitum o......
Early afterdepolarization (EAD) in mouse atrial fibers was investigated under the treatment with aconitine, 3. 0 mmol/L ......
The mammal gut microbiota has been called“a hidden-organ”.About 99%of the intestinal bacteria belong to anaerobic bact......
[Objective] The experiment aimed to explore the relations between structure of aconitine, aconitine derivatives and inse......
从草乌——北乌头(Aconitum kusnezoffii Reichb.)的块根——中分离得到16个单体成分,据波谱方法分别鉴定为:乌头碱(aconitine,1)......
An electrospray ionization / tandem mass spectrometric (ESI/MS/MS) method was developed for the simultaneous identificat......
A new franchetine-type C19-diterpenoid alkaloid 3-hydroxyfranchetine 1 and a new aconitine-type C19-diterpenoid alkaloid......
Investigation of Aconitine-type Alkaloids from Processed Tuber of Aconitum carmiechaeli by HPLC-ESI-
Introduction Aconitine-type alkaloids isolated from the roots of Aconitum carmiechaeli show a potential toxicity and a b......
目的:探究止痛温经散中乌头碱经皮给药的血药浓度的测定及安全性.方法:将12只小鼠平均分为对照组与敷药组,对照组不进行处理,敷药......
目的:探讨不同浓度的黄芪甲苷对乌头碱诱导的斑马鱼心脏损伤的保护作用.方法:挑选受精后发育正常的48 h斑马鱼胚胎,用30 mg/L的乌......
Inhibition of the INa/K and the activation of peak INa contribute to the arrhythmogenic effects of a
Aconitine(ACO),a main active ingredient of Aconitum,is well-known for its cardiotoxicity.However,the mechanisms of toxic......
ANTAGONISM OF TOTAL FLAVONES OF GYNOSTEMMA PENTAPHYLLUM (THUNB) MAK TO ANIMAL EXPERIMENTAL ARRHYTHMI
The action of total flavones of Gynostemma pentaphyllum (Thunb) Mak (TFG) 60 mg/kg i.v. could prevent arrhythmias induce......
环磷酰胺在临床上广泛用于治疗各种肿瘤,然而环磷酰胺可显著降低白细胞、血小板、红细胞以及血红蛋白的水平,导致严重的骨髓抑制,......
将脂质体作为模拟生物膜,采用平衡透析法与紫外分光光度法研究附子提取液中乌头碱与脂质体的相互作用,并考察了薄膜分散法、乙醇注......
Chinese herbal medicines have been extensively used in China and other countries for cen-turies.Aconitine,a diterpenoid ......
Aim: The present work was designed to investigate the relationship between hemodynamic parameters and the susceptibility......
,Discovery of N-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide (sulcardine)
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Limitation standard of toxic aconitines in Aconitum proprietary Chinese medicines using on-line extr
Development of rapid analytical methods and establishment of toxic component limitation standards are of great importanc......
本文通过对荣华二采区10...
目的采用HPLC法测定黄毛翠雀花中乌头碱、新乌头碱和次乌头碱的含量。方法采用Aglient Eclipse XDB-C18色谱柱(150 mm×4.6 mm,5μ......
目的研究白喉乌头Aconitum leucostomum Worosch.中的生物碱。方法采用柱色谱法分离纯化得到单体化合物,通过多种波谱方法鉴定其结......
