Senescence相关论文
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Significant cellular senescence has been observed in cartilage harvested from patients with osteoarthritis(OA).In this s......
结直肠癌(CRC)是一种高度侵袭性的恶性肿瘤，在全球范围内，其发病率和死亡率分别位居第3位和第2位。近年来，免疫检查点抑制剂(ICIs)的......
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This report introduces the background of button mushroom and its classification,reviews the history and development of m......
MicroRNAs and targets in senescent litchi fruit during ambient storage and shelf life after cold sto
Background: Litchi deteriorates with the pericarp turning brown within 1-2 days after harvest.MicroRNAs act as negative ......
A putative PPR gene Esl1 is essential for plant active growth and negatively regulates innate immuni
Maintaining active growth and effective immune responses pathogens is crucial for a living organism to survive.In rice, ......
Winter and spring nighttime warming acclimation improves the grain yield of winter wheat via enhanci
Impacts of asymmetric warming on wheat remain uncertain.To investigated the response of wheat to the moderate warming, w......
A Soybean Dual-specificity Kinase GmSARK and Its Arabidopsis Homologue AtSARK Regulate Leaf Senescen
As the last stage of leaf development,senescence is a fine-tuned process regulated by interplays of multiple signaling p......
In order to explore the genetics of dark-induced senescence in winter wheat(Triticum aestivum L.), a quantitative trait ......
Acid-sensingionchannel1aregulatesthesurvivalofnucleuspulposuscellsintheacidicenvironme
Activationofacid-sensingionchannel1a(ASIC1a)isresponsiblefortissueinjurycausedbyacidosisinnervoussystems.......
Astragalus polysaccharide attenuated iron overload-induced dysfunction of mesenchymal stem cells via
Background/Aims:Bone marrow-derived mesenchymal stem cells(BMSCs)have the ability to differentiate into multilineage cel......
目的 To explore the late effect of total body irradiation on small intestine 方法 Mice were exposed to 8Gy total body ir......
In this study,we exposed adult aged rats to a chronic variable stress model and compare astroglial changes as a function......
Lysophosphatidic Acid and Adenylyl Cyclase Inhibitor Modulate Phosphorylation of AMP-Activated Prote
Senescent human diploid fibroblasts (HDFs) were reported to be mostly insensitive to mitogenic stimuli.However,we found ......
Aim: Nonalcoholic fatty liver disease (NAFLD) is characterized by macrovesicular hepatic steatosis and chronic inflammat......
Blockade of IL-1 7A attenuates renal fibrosis through inhibiting the IL17A-participated tubular epit
Renal fibrosis is the common and final histopathological feature for many kidney diseases.IL-17A has recently been shown......
Aim Aging is an independent risk factor for heart disease, however the effective intervention has not been found so far.......
DNA double-strand-breaks (DSBs) are the most serious DNA damage, which can be repaired mainly by two pathways, namely ho......
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SARK(senescence-associated receptor-like kinase)family members in Arabidopsis,soybean and rice are known to be a positiv......
Maintaining active growth and effective immune responses pathogens is crucial for a living organism to survive.In rice, ......
The Role of Hippocampal structural synaptic plasticity in repetitive transcranial magnetic stimulati
Objective Repetitive transcranial magnetic stimulation (rTMS) could improve the cognitive functions in patients with Alz......
TGF-β and NF-κB signaling pathway crosstalk potentiates ocular cellular senescence via an RNA stress
Purpose We investigated the age-related senescent phenotype in the normal corneal epithelium and the role of TGF-β in c......
PC2 safeguards human mesenchymal stem cells from premature senescenceby counteracting nucleolar stre
Human mesenchymal stem cells (hMSCs) exhaustion is considered as one of the main reasons for human physiological aging a......
p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and s
The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor suppressing property......
TaSCL14, a novel wheat (Triticum aestivum L.) GRAS gene, regulates plant growth, photosynthesis, tol
GRAS protein, named after the three members GIBBERELLIC ACID INSENSITIVE (GAI), REPRESSOR of GA1 (RGA) and SCARECROW (SC......
Observation about time-effect relation of extracts from ginseng notoginseng and chuanxiong on vascul
Objective: To observe the time-effect relation of extracts from ginseng notoginseng and chuanxiong on angiotensin Ⅱ-ind......
Mitofilin rescues deficiency in differentiation potential of mesenchymal stem cells in senescent ost
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CDC6 is a Novel Switch of Radiation-Induced Senescence,Apoptosis and Epithelial and Mesenchymal Tran
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CPEB1,a histone-modified hypomethylated gene,is regulated by miR-101 and involved in cell senescence
Epigenetic mechanisms play important roles in carcinogenesis.We certifiedthat the mRNA translation-related genecytoplasm......
Functional Phosphoproteomic and Genetic Analysis of Molecular Mechanism Underlying Ethylene-Regulate
Ethylene is a widely-accepted senescence hormone in higher plants.It promotes leaf-yellowing,leaf and flower petal absci......
REAL-TIME FLUORESCENCE IMAGING OF SIRT1 CYTOSOLIC TRANSLOCATION UNDER THE TREATMENT OF GROWTH FACTOR
Sirtuins comprise a family of enzymes implicated in the determination of organismal lifespan in yeast and the nematode. ......
Epstein-Barr virus induces human nasopharyngeal epithelial cells to escape from the replicative sene
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目的研究小鼠衰老耳蜗血迷路屏障通透性的变化，并通过建立内皮细胞（endothelial cells，EC）系和周细胞（pericytes，PC）系非接触式共培养模型......
目的探讨健康人群外周血淋巴细胞Pole2表达水平的增龄性变化，分析常见4种老年病患者与同龄正常人外周血淋巴细胞Pole2表达水平的差......
Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTER
Oxidative st ress is bel ieved to be an import ant inducer ofc e l lular senescence and aging.Zinc finger protein 63......
A Human Stem Cell Model of Werner Syndrome Reveals Novel Genomic and Epigenomic DysregulationDuringA
Werner syndrome (WS) is a premature aging disorder caused by genetic mutations in the RecQ DNA helicase WRN.The mole......
Mitochondrial protease gene FtSH4 involves in autophagy by regulating WRKYs-dependent salicylic acid
Mitochondria and autophagy play important roles in the networks that regulate plant leaf senescence and cell death.H......
Suppression of c-Myc oncogene was reported to prompt cell senescence leading to carcinogenetic arrest in many tumors.Pre......
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Localization shifting of WHIRLY1 leads to the change of JA, SA or ETH and Arabidopsis senescence and
Plant endogenous hormones, growth environment and nutrition control plant development, formation and senescence proc......
Calcium signaling plays an essential role in plant cell physiology, and chaperone-mediated protein folding directly ......
Induction of autophagy and senescence by knockdown of ROC1RBX1 E3 ubiquitin ligase to suppress the g
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Plasminogen activator inhibitor-1(PAI-1)is a member of the evolutionarily conserved serine pro⁃tease inhibitor family.T......
Objective: RECQL4 (a member of the RECQ helicase family) upregulation has been reported to be associated with tumor prog......
FGFR/RACK1 interacts with MDM2, promotes P53 degradation, and inhibits cell senescence in lung squam
Objective:FGFR is considered an important driver gene of lung squamous cell carcinoma(LSCC).Thus,identification of the b......
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