histones相关论文
Aim: To examine the relationship between sperm DNA damage and sperm nuclear histone (H2B) staining. Methods:We evaluated......
Retrospective descriptive analysis of the physiological kinetics of prostate-specific antigen in men
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HDACs play important roles in regulating various physiological and pathological processes.Developing fluorescent probes ......
Glial fibrillary acidic protein levels are associated with global histone H4 acetylation after spina
Emerging evidence has suggested global histone H4 acetylation status plays an important role in neural plasticity. For i......
目的探讨磷酸化组蛋白H3(PHH3)和β-连环素(β-catenin)在非小细胞肺癌(NSCLC)组织中的表达及临床意义。方法收集日照市中心医院20......
目的了解亚砷酸钠(NaAsO2)对人皮肤角质形成细胞(HaCaT细胞)组蛋白H3第36位赖氨酸三甲基化(H3K36me3)修饰水平、O6-甲基鸟嘌呤DNA甲基转......
目的 探讨低剂量无机砷对人正常肝细胞(L-02)中Sirt1及细胞周期相关基因表达的影响.方法 0.0(对照)、0.1、0.2、0.4 μmol/L三氧化......
目的探讨血浆组蛋白预测脓毒症患者预后的应用价值。方法选择2016年5月至2018年6月扬州大学附属江苏省苏北人民医院重症医学科(ICU)......
目的 探索脊髓p300在大鼠慢性缩窄性神经损伤(CCI)模型所致神经病理性疼痛中的作用.方法 32只雄性SD大鼠随机分为假手术组(Sham组)......
目的了解亲代酒精暴露诱导的组蛋白修饰改变是否遗传给子代,探讨亲代酒精暴露对子代的酒精觅药行为影响的表观遗传机制。方法24只雄......
Growth inhibition and gene induction in human hepatocellular carcinoma cell exposed to sodium 4-phen
Background Sodium 4-phenylbutanoate (NaPB) can induce cellular differentiation and cell cycle arrest.However,its potenti......
[目的]评价组蛋白去乙酰化酶( HDAC)抑制剂 Depsipeptide 对肺腺癌细胞株 H1299的生长抑制作用及机制.[方法]分别以体外药物敏感试......
核组蛋白2在丘脑下部核及许多外周组织均有表达,其信号通路的研究尚不完善,神经内分泌调节、细胞存活增长、肿瘤抑制及细胞因子分泌......
Growth inhibition and gene induction in human hepatocellular carcinoma cell exposed to sodium 4-phen
Background Sodium 4-phenylbutanoate (NaPB) can induce cellular differentiation and cell cycle arrest.However,its potenti......
Dinoflagellates are a very large and diverse group of eukaryotic algae that play a major role in aquatic food webs of bo......
目的探索弥漫性中线胶质瘤,H3 K27M突变型,WHOⅣ级的新型治疗方法。方法与结果女性患者,51岁,病理确诊为弥漫性(左侧额叶、丘脑)中......
目的射频消融术(radiofrequency ablation,RFA)已成为治疗肝癌的主要手段,但RFA亦可导致明显的炎症反应,影响临床治疗和预后。细胞外......
目的探讨茶碱联合红霉素对慢性阻塞性肺疾病(COPD)大鼠的抗炎作用及对组蛋白去乙酰化酶2(HDAC-2)的影响。方法雄性SD大鼠50只,随机......
表观遗传学参与调节精子发生和精子形成,其中组蛋白及非组蛋白乙酰化对生精细胞染色质结构重建以及精子活力起关键作用。环磷酸腺......