Neuroprotection相关论文
Pterostilbene attenuates high glucose-induced oxidative injury in hippocampal neuronal cells by acti
In the present study,neuroblastoma（SH-SY5 Y）cells were used to investigate the mechanisms mediating the potential protecti......
Exploring the role of interleukin-27 as a regulator of neuronal survival in central nervous system d
Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell stress, neuronal diseas......
Prolactin is a polypeptide hormone associated with an extensive variety of biological functions. Among the roles of prol......
Stress response is a cellular widespread mechanism encoded by a common protein program composed by multiple cellular fac......
Spinal cord injury (SCI) research is a very complex field lending to why reviews of SCI literatures can be beneficial to......
SRY-related HMG-box (Sox) transcription factors are known to regulate central nervous system development and are involve......
Schwann cells differentiated from skin-derived precursors provide neuroprotection via autophagy inhi
Autophagy has been shown to play an important role in Parkinson\'s disease.We hypothesized that skin-derived precursor......
Our previous study has shown that the transcription factor Krüppel-like factor 7 (KLF7) promotes peripheral nerve regen......
Enhanced treatment for cerebral ischemia-reperfusion injury of puerarin loading liposomes through ne
The recovery of blood circulation following cerebral infarction-associated thrombolysis brings new damage to the brain,w......
Stroke is considered a leading cause of mortality and neurological disability,which puts a huge burden on individuals an......
内质网应激(endoplasmic reticulum stress,ERS)与帕金森病(Parkinson\'s disease,PD)发展进程密切相关.Apelin是已被证实具有明......
Glycogen synthase kinase-3β (GSK-3β) has been shown to attenuate DNA damage in nerve cells, thereby enhancing neuronal......
Physiopathology of ischemic stroke and its modulation using memantine: evidence from preclinical str
Ischemic stroke is the most common type of cerebrovascular disease and is causedby an interruption of blood flow in the ......
Bcl-xL is a pro-survival protein of the Bcl2 family found in the mitochondrial membrane. Bcl-xL supports growth, develop......
Parkinson\'s disease is a neurodegenerative disorder characterized by a combinationof severe motor and non-motor sympt......
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfu
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) ......
Pretreatment with Baicalin Attenuates Hypoxia and Glucose Deprivation-Induced Injury in SH-SY5Y Cell
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Gastrodin is a phenolic glycoside that has been demonstrated to provide neuroprotection in preclinical models of central......
MicroRNA-365 Knockdown Prevents Ischemic Neuronal Injury by Activating Oxidation Resistance 1-Mediat
MicroRNA-365 (miR-365) is upregulated in the ischemic brain and is involved in oxidative damage in the diabetic rat.Howe......
α-Synuclein is a soluble monomer abundant in the central nervous system.Aggregates of α-synuclein,consisting of higher......
Currently there are no convincing effective treatments for spinal cord injury(SCI),meanwhile,factors that adversely affe......
Investigating the mechanism of action of ethoxyquin as a neuroprotection drug against peripheral neu
Ethoxyquin(EQ(1,2-dihydro-6-ethoxy-2,2,4,trimethylqyuinoline))is an antioxidant used in animal foods for over 50 years.I......
Etidronate and trisphosphonates are new potential candidates for neuroprotective drugs for Alzheimer
Objective Bisphosphonates(BP)is a category of drugs that are used to treat various bone diseases,such as osteoporosis,Pa......
HSP-72confers protection in retinal ganglion cells and lateral geniculate nucleus neurons via blocka
Objective To indicate that heat shock protein 72(HSP72)is involved in the prevention of neuronal injury.Method Zinc sulf......
The effect of mesenchymal stem cells on retinal ganglion cell-5 and endoplasmic reticulum stress pat
Purpose Apoptosis of retinal ganglion cells(RGCs)is one of the common pathological features associated with optic nerve ......
Moderate alcohol preconditioning activates neuronal BKCa channels to protect brain damage-induced by
Objective Stroke is the third most common cause of death after heart attack and cancer and has profound negative social ......
Up-regulated expression of NT-3 mediated by hypoxia response element attenuates cerebral ischemia/re
To investigate the neuroprotective effects of neurotrophin-3(NT-3) expression controlled by five copies of the hypoxia-r......
Methylene blue(MB)was mainly used in the clinical treatment of cyanide poisoning and methemoglobinemia.Currently,the neu......
Preconditioning with recombinant HMGB1 induces ischemic tolerance in a rat model of focal cerebral i
Preconditioning means that a previous minor insult prepares the body to better withstand a subsequent larger insult.High......
Calorie restriction (CR) not only extends lifespan of organisms but also increases resistance to a variety of age-relate......
Caloric restriction(CR)has been shown to have several health benefits and provides protection against type 2 diabetes,ne......
Deproteinised Calf Blood Injection(DCBI)has been used in neurology as a neuroprotective agent,but little research about ......
Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation
Glial cell response to injury has been well documented in the pathogenesis after traumatic brain injury(TBI)and spinal c......
Fast nongenomic neuroprotection mediated by GPR30-dependent depression of NR2B-containing NMDA recep
17-β-Estradiol (E2) is a steroid hormone involved in neuroprotection against excitotoxicity and other forms of brain in......
The Behavioral Study on the Neuroprotection of GLP-1/GIP/GCG Receptor Triagonist in Triple-transgeni
Objective Alzheimers disease(AD)is a progressive neurodegenerative disorder which is still irreversible up to now.The ty......
Shengmai injection attenuates ischemia-reperfusion-induced autophagy correlating to modulating AMPK,
Aim Shengnai injection (SMI) , a Chinese patent medicine deprived from an ancient Chinese herbal compound Shengmai san, ......
Cerebroprotection by hesperetin is associated with restoration of tryptophan metabolic enzyme system
Aim: The tryptophan metabolic enzyme systems of indoleamine 2,3-dioxygenase (IDO) and tryptophanyl-tRNA synthetase (TrpR......
Influence of the focal ischemia reperfusion on a novel estrogen receptor alpha 36 and correlated est
Aim: Previous studies showed that ER-α36, a novel variant of estrogen receptor alpha (ER-α) was widely expressed in br......
Aim: Sildenafil, a phosphodiesterase type 5 inhibitor, has been found to produce functional recovery in ischemic rats by......
The neuroprotection of 17β-estradiol: a modulated mechanism of TLR2 in oxidative stress induced apop
Objective: toll-like receptors (TLRs) could mediate innate and adaptive immunity and also could be affected by oxidative......
Ursolic Acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice
Background:Oxidative and inflammatory damage have been suggested to play an important role in cerebral ischemic pathogen......
Sphingosine kinase-2 induced autophagy activation mediates ischemic tolenrance in primary cortical n
Aim This study is aimed to determine whether SPK2 (Sphingosine kinase2) is involved in isoflurane preconditioning induce......
Neuroprotective activity of Shengnaokang Preparation against cerebral ischemia/reperfusion-induced i
Aim: Shengnaokang preparation (SP), consisting of fifteen Chinese herbal medicines, has been used for the treatment of c......
Neuroprotection of saponins from Panax japonicus against D-galactose-induced senescence via activati
Aim: Increasing evidence indicates that oxidative stress plays a key role in the senescent development.NF-E2-related fac......
Inhibition of autophagy aggratated oxygen-glucose deprivation/reperfusion induced neuron injury in v
Objective Several lines of evidences indicated that autophagy was involved in ischemic brain injury.Ischemia/reperfusion......
Anti-Parkinsonian effects of Polygonum multiflorum Thunb.on transgenic and pharmacological Caenorhab
Objective: Polygonum multiflorum Thunb.is more commonly used in Chinese herbs/constituents (e.g.Kang Zhen Zhi Jing No.1 ......
