The pharmaceutical quality control is of great importance for maximizing the efficacy and the safety of the drug therapy......

...

目的:制备可实现持续多巴胺能刺激治疗帕金森病的罗替戈汀缓释微球,并进行体内外评价。方法:采用O/W乳化溶剂挥发法制备微球,并对......

Objective: Levodopa is the gold-standard of therapy in Parkinson’s disease (PD), but it is associated with motor compli......

以5-甲氧基-2-萘满酮(II)为原料,经缩合、还原、拆分、去甲基等反应制备了(S)-1,2,3,4-四氢-5-羟基-N-丙基-2-萘胺(I)。就I合成的......

Background: Parkinson’s disease (PD) is a progressive neurodegenerative disease that occurs as a result of loss of dopa......

Background: Parkinson’s disease (PD) is a progressive neurodegenerative disease that occurs as a result of loss of dopa......

...

...

在一项双盲、多中心研究中，rotigotine（Neupro，SPM962）（Ⅰ）透皮贴剂可有效治疗中至重度自发性不宁腿综合征（IRLS）。这项摸索剂量研究收入37......

Neupro经皮系统是一种设计用于治疗早期帕金森病（PD）的硅烷基贴剂，从未在美国被批准过。它是第一个获准用于治疗PD症状的贴剂。Rotigo......

罗替戈汀由德国施瓦茨公司(Schwarz Biosciences)研制,用于早期继发性帕金森病和晚期帕金森病的辅助治疗,商品名为Neupro。2007年5......