salvicine相关论文
目的:合成和鉴定聚乙二醇化聚氰酯共聚物,制备聚乙二醇化聚氰酯共聚物和聚氰酯聚合物的毫微粒,测定二种毫微粒的体外特性。方法:用......
目的:确定DNA拓扑异构酶Ⅱ(Topo Ⅱ)是否为salvicine在酿酒酵母细胞内的主要作用靶点及其作用方式。方法:用Topo Ⅱ介导的超螺旋pB......
,Salvicine,a novel topoisomerase Ⅱ inhibitor, exerts its potent anticancer activity by ROS generatio
Salvicine is a novel diterpenoid quinone compound obtained by structural modi-fication of a natural product lead isolate......
Systematic structure modification of the side train of the lead compound saprothoquinone provides a series of salvicine ......
肿瘤多药耐药(multidrug resistance，MDR)是临床化疗成功最为严重的障碍．首先阐明了新拓扑异构酶II抑制剂沙尔威辛对MDR肿瘤细胞直接......
目的：探讨Salvicine在细胞和分子水平抑制血管生成的作用及机制。方法：采用改良MTT法、内皮细胞迁移和小管形成实验等方法检测Salvic......
