theophylline相关论文
An intriguing electrochemical impedance aptasensor based on a porous organic framework supported sil
Porous organic frameworks (POFs) are excellently stable porous materials,which can be employed as host platforms to supp......
目的 Chronic obstructive pulmonary disease(COPD)phenotypes may have individual characteristics and different responses t......
Respiratory Effects in the Sprague DawleyRatfollowing Single Oral Administration of Theophylline and
Aim Assessment of respiratory safety is one of the most important requirements for new chemical entity(ICH and Chinese G......
Inhibitory effect of baicalin on the plasma protein binding and CYP1A2 activity induce the pharmacok
Aim: To elucidate the effect of baicalin on the pharmacokinetics of theophylline in rats, focusing on plasma protein bin......
A novel and simple molecularly imprinted polymer (MIP) based electrochemical sensor was developed.Dopamine,used as a fun......
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heophylline (THO) molecular imprinted composite membranes (MIM) were successfully fabricated by thermal initiated fr......
目的研究茶碱缓释片联合噻托溴铵干粉治疗稳定期慢性阻塞性肺疾病(COPD)的临床疗效。方法将140例稳定期COPD患者，按照随机数字表法......
目的比较加倍剂量吸入激素与吸入激素联合茶碱治疗哮喘的临床效果。方法选取哮喘患者64例，按照治疗方案的不同将其分为观察组和对照......
目的观察吸烟支气管哮喘患者吸入小剂量糖皮质激素联合茶碱治疗的疗效。方法选取门诊支气管哮喘患者73例，其中吸烟患者34例（观察组），非......
Quantification of theophylline or paracetamol in milk matrices by high-performance liquid chromatogr
A simple, accurate and sensitive high-performance liquid chromatography (HPLC) method was developed, validated and appli......
1例63岁、有10年慢性阻塞性肺疾病史的女性患者从2013年1月至2015年1月口服复方妥英麻黄茶碱片2片，3次/d。2014年4月(用药16个月)首......
1例79岁女性患者，因慢性阻塞性肺疾病口服复方妥英麻黄茶碱片2片，2次/d。用药2个月间断出现头面部不自主运动；用药9个月间断出现头晕，......
目的用失效模式和效应分析(FMEA)法探讨静脉用茶碱类药物管理过程发生用药错误的风险点，改进管理措施，提高用药安全性。方法应用FMEA......
目的观察小剂量布地奈德联合茶碱缓释片干预性治疗婴幼儿喘息发作的疗效。方法将90例毛细支气管炎患儿随机分为观察组和对照组各45......
目的 评价噻托溴铵联合缓释茶碱治疗中度稳定期慢性阻塞性肺疾病(COPD)的临床疗效及其安全性.方法 将我院2008年3月至2009年12月收......
Molecularly Imprinted Polymer Theophylline Retention and Molecular Recognition Properties in Capilla
Molecular imprinting of theophylline in poly (methacrylic acid- ethylene dimethacrylate) as CEC stationary phases was sy......
目的建立咳喘宁合剂中茶碱含量测定方法。方法色谱柱为Agilent TC-C18柱(250 mm×4.6 mm,5μm),流动相为甲醇-水(25∶75),检测波长......
目的分析氟喹诺酮类与茶碱类联用致不良事件的特点,为临床合理用药提供参考。方法检索Pub Med、CNKI、VIP、CMB和万方数据有关氟喹......
目的观察小剂量茶碱联合沙美特罗氟替卡松50μg/250μg治疗中重度稳定期慢性阻塞性肺疾病(COPD)的疗效和安全性,并与单独吸入沙美......
目的建立HPLC测定复方氨肽素片中氨茶碱与马来酸氯苯那敏的含量及含量均匀度。方法色谱柱为YMC Hydrosphere C18(4.6 mm×250 mm,5......
目的研究丹参酮ⅡA对大鼠体内茶碱药动学特征的影响。方法将24只大鼠随机分成3组,Ⅰ组:生理盐水,ip×7 d;Ⅱ组:丹参酮ⅡA 7 mg·kg......
目的建立一种运用拉曼光谱技术快速测定氨茶碱注射剂中无水茶碱和乙二胺的方法。方法采用拉曼光谱技术对3种规格的氨茶碱注射剂直......
目的建立HPLC法测定早产儿血清中茶碱的浓度,并将其应用于我院早产儿血药浓度监测。方法咖啡因作内标,血样经液-液萃取后,取有机相......
,Interleukin-12 was not involved in promotion of T helper cell differentiation induced by theophylli
AIM: To investigate the effect of theophylline on the naive T cell differentiation and the probable role of interleukin1......
,Modulation of pharmacokinetics of theophylline by antofloxacin, a novel 8-amino-fluoroquinolone, in
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目的:研究脉络宁注射液对大鼠CYP1A2、CYP2E1和CYP3A4活性的影响.方法:14只大鼠随机均分成临床等效剂量组和高剂量组,连续2周静脉......
目的：研究茶碱缓释片联合噻托溴铵干粉吸入对中重度缓解期慢性阻塞性肺疾病(COPD)患者的临床疗效。方法将本院58例中重度缓解期COPD......
Objective To determine the prevalence of sleep-disordered breathing in patients with stable, optimally treated chronic ......
Background Chronic intermittent hypoxia (CIH) has been associated with abnormalities in the liver,which is the most impo......
目的采用HPLC法同时测定慢性阻塞性肺病(COPD)患者血浆中的茶碱及其代谢物1,3-二甲基尿酸(1,3-DMU)。方法色谱柱为Hypersil BDS C1......
Simultaneous Determination of Caffeine and Theophylline in Human Plasma with a Weak Cation Monolithi
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Evaluation of airway function and inflammation after theophylline controlled release tablet combined
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 研究小剂量茶碱、西替利嗪口服联合小剂量激素吸入对哮喘的治疗效果.方法 将48例轻、中度哮喘患者用抽签法随机分成2组,各24......
茶碱因其支气管扩张作用而应用于临床多年,目前对其抗炎作用及机制有了一些新认识.茶碱可提高细胞内的磷酸腺苷浓度、拮抗腺苷受体......
茶碱类支气管舒张药价格便宜、使用方便,但治疗剂量与中毒剂量接近限制了其临床应用,近年研究表明小剂量茶碱除具有支气管舒张作用......
目的 应用计算机视频跟踪技术,探讨中枢兴奋药茶碱和咖啡因对小鼠自发活动行为特点的影响.方法 KM鼠分别腹腔注射不同剂量的茶碱和......
Theophylline has been widely used in the treatment of airway disease but molecular mechanism has not been clearly elucid......
Objective: This study aimed to establish chemiluminescent immunoassay (CLIA) for quantitative determination of theophyll......
Chitosan and a-cyclodextrin were used to prepare microspheres with theophylline for pulmonary delivery by spray drying m......
In the present work, the equilibrium adsorption of theophylline was studied by phenolic resin adsorbents: JDW-2(made by ......
A mathematical model of the dynamic behavior of countercurrent chromatography was proposed, and the model parameters, in......
目的研究分析针对老年哮喘疾病患者临床中采取糖皮质激素联合茶碱治疗的综合效果。方法筛选出医院于2018年1月—2019年6月期间接收......
目的探讨不同剂量茶碱联合吸入治疗对重度慢性阻塞性肺疾病(COPD)的疗效。方法将2018年7月至2019年5月该院门诊就诊的60例重度稳定......
目的探讨小剂量糖皮质激素(GC)联合茶碱治疗支气管哮喘的临床效果。方法选择2018年4月~2019年4月大连大学附属中山医院收治的80例......
目的：通过研究腺苷、白细胞介素(IL)-1及茶碱对哮喘患者外周血单个核细胞(PBMCs)A3腺苷受体(A3AR)mRNA表达的影响，探讨A3AR在哮喘发......
目的：观察茶碱治疗前后哮喘患者诱导痰IL-6水平的变化。评价1L-6与哮喘发病的关系。方法：选择支气管哮喘患者60例随机分为茶碱治疗组......
运用荧光光谱法研究了茶碱与牛血清白蛋白(BSA)的相互作用。实验结果表明,茶碱与BSA形成基态复合物导致BSA内源荧光猝灭,猝灭机理......
目的：分析吸入糖皮质激素联合茶碱与联合长效β2受体激动剂治疗哮喘的效果。方法：收治支气管哮喘急性发作患者98例，随机分成两组，均给......
