【摘 要】
:
Chemical synthesis is essential to natural products research not only for supply of sufficient material but for the structure confirmation.Eleganketal A, a naturally occurring aromatic polyketide poss
【机 构】
:
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocea
【出 处】
:
中国化学会第十届全国天然有机化学学术会议
论文部分内容阅读
Chemical synthesis is essential to natural products research not only for supply of sufficient material but for the structure confirmation.Eleganketal A, a naturally occurring aromatic polyketide possessing a rare highly oxygenated spiro[isobenzofuran-l,3-isochroman] ring system, was isolated from the fungus Spicaria elegans KLA03.
其他文献
Phytochemical study on the whole plant of Borreria latifolia led to the discovery of two new compounds, 3β,6β,23-trihydroxyursa-12,20(30)-dien-28-oic acid (1) and 3β,6β,30-trihydroxy-olean-12-en-28-oi
Marine fungi have developed their unique metabolic system to adapt the special marine environment.Their novel metabolites have enlarged the diversity of organic compounds and have shown exciting and u
25-OH-PPD1 (25-hydroxyprotopanaxadiol), a promising antitumor natural compound isolated from the fruits of Panax ginseng, could inhibit cancer cell proliferation, caused cell cycle arrest in vitro and
Gracilamine1 is a new member of the amaryllidaceae alkaloid family, and it can also be regarded as an aminal derivative of hydrofluorenone containing natural products (rings A-C).In this presentation,
异戊烯基酚性化合物是一类重要的植物次生代谢产物,具有广泛的生理活性,包括抗肿瘤、抗氧化、酪氨酸酶抑制、胰脂酶抑制、组织蛋白酶抑制等.桑科波罗蜜属(Artocarpus)植物是该类成分的一个重要来源.本课题组对两种波罗蜜属植物(A.styracifolius和A.heterophyllus)中的异戊烯基酚性成分进行了较系统的研究,目前获得了30多个异戊烯基酚性化合物,其中新化合物18个.新化合物种类
随着全球经济的快速发展,生活水平的日益提高,高热量高脂肪食物的过多摄入,以及体力劳动的减少,肥胖症的发病率与日俱增.据不完全统计,目前全世界肥胖症发病人数已近5亿,每年因肥胖症促成的直接或间接死亡人数达30万,并有可能成为21世纪的头号杀手.随着人类基因组测序的完成,寻找导致肥胖的遗传因素是目前科学界研究的热点问题.FTO (Fat Mass and Obesity Associated)基因是目
Camptothecin (CPT) and its related analogues represent an important class of agents useful in the treatment of cancer1.Structure-activity relationship (SAR) studies showed that the ring E lactone and
3-Benzylidene-indolin-2-one derivatives are a novel kind of alkaloids possessing a wide range of biological activities, such as anti-inflammation, anti-tumor, antiproliferation, tyrosine kinase inhibi
紫檀芪(pterostilbene,1)是一种存在于紫檀、蓝莓、黑莓等多种植物中的天然产物,它具有抗癌、抗氧化等生物活性,其抗肿瘤细胞增殖作用比白藜芦醇强1-3.含氮的Mannich碱结构单元是一类重要的药理活性基团,并可以有效提高化合物的生物活性及水溶性4,5.我们以3,5-二羟基苯甲酸、对羟基苯甲醛或香草醛为原料,以Wittig-Horner反应为关键步骤,合成得到天然产物紫檀芪(1).以1为
The pyrrole nucleus as a prevalent heterocyclic structure is embedded in biologically active natural products, synthetic pharmaceuticals1 and they also widely existed in material science, solar batter