Synthesis and antitumor activity of novel substituted uracil-1'(N)-acetic acid ester derivative

来源 :中国化学会第十届全国天然有机化学学术会议 | 被引量 : 0次 | 上传用户:zhongyuzhang09
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Camptothecin (CPT) and its related analogues represent an important class of agents useful in the treatment of cancer1.Structure-activity relationship (SAR) studies showed that the ring E lactone and the natural 20S-configuration of camptothecins are essential for antitumor activity.
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