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High hydrostatic pressure (HHP) was applied for pectin extraction from navel orange peel in this study.The effects of three parameters, including pressure, temperature, and pressure-holding time, on the extraction yield and viscosity of pectin were studied.A 2-factor 3-level design, following a single-factor experiment, was carried out to optimize the extraction parameters and the optimal condition of HHP extraction was determined: pressure 500 MPa, temperature 55 ℃, pressure-holding time 10 min.