【摘 要】
：
The chemical similarity of cellulose and chitin supports the idea that their corresponding hydrolytic enzymes would bind β-1,4-1inked glucose residues in a sim
【机 构】
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大连理工大学生命科学与技术学院,大连116024大连理工大学软件学院,大连116024中国科学院上海药物研究所,上海201203
【出 处】
：
第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会
论文部分内容阅读
The chemical similarity of cellulose and chitin supports the idea that their corresponding hydrolytic enzymes would bind β-1,4-1inked glucose residues in a similar manner.A structural and mutational analysis was performed for the plant cellulolytic enzyme BGlu1 from Oryza sativa and the insect chitinolytic enzyme OfHex 1 from Ostrinia furnacalis.Although BGlul shows little amino-acid sequence or topological similarity with Of Hex 1, three residues (Trp490, Glu328, Va1327 in OfHex1, and Trp358, Tyr131 and Ile179 in BGlu1) were identified as being conserved in the +1 sugar binding site.
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