Endothelin-converting enzyme-1 regulates the re-sensitisation of signalling by the glucagon-like pep

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：damoxian

【摘要】

：

Aim: Endothelin-converting enzyme-1 (ECE-1) may regulate trafficking of internalized GPCRs by degrading peptide ligands in endosomes.We examined the impact of ECE-1 on re-sensitisation of the glucagon

【作者】

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Jing LU Gary B WILLARS

【机构】

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Department of Cell Physiology and Pharmacology, University of Leicester, Leicester, LE1 9HN, United

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

：

GLP-1 ECE-1 receptor trafficking

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Endothelin-converting enzyme-1 regulates the re-sensitisation of signalling by the glucagon-like pep

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