No association between PON1 gene single nucleotide polymorphisms and clopidogrel resistance in Chine

来源 :2013中国心脏大会(CHC) | 被引量 : 0次 | 上传用户:jonelove0000
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Background Clopidogrel requires bioactivation in vivo to convert the pro-drug into its active metabolite to show its antiplatelet effects.The variability in the clinical response to clopidogrel treatment has been attributed to genetic factors,but specific genes and mechanisms underlying clopidogrel bioactivation remain unclear.
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