Stimuli-responsive nanocarriers based on mesoporous silica nanoparticles and magnetic iron nanoparti

来源 :中国微米纳米技术学会纳米科学技术分会第三届年会暨2014全国纳米生物与医学学术会议 | 被引量 : 0次 | 上传用户:zhuzihai
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  Construction of stimuli-responsive controlled release system for targeted drug delivery to specific cells is essentially important for cancer therapy since most chemotherapeutics are severely toxic [1].Surface-functionalized magnetic nanoparticles(MNPs)and end-capped mesoporous silica nanoparticles(MSNs)presented themselves as ideal stimuli-responsive carriers for controlled drug and/or gene delivery,owing to their good biocompatibility,tunable sizes and large surface areas.To trigger drug release via signals derived from cells and to confirm the biosaftey of MSNs-based system attracted much attention in the related field.
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