The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK22

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：shensq

【摘要】

：

Cap-dependent translation is a potential cancer-related target (oncotarget) due to its critical role in cancer initiation and progression.

【作者】

：

Hongtao Wang Fang Huang Jian Wang Peng Wang Wenjie Lv Liu Hong Shanhu Li Jianguang Zhou

【机构】

：

Laboratory of Medical Molecular Biology, Beijing Institute of Biotechnology, Beijing, 100850;State K

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

Cap-dependent translation 4EGI-1 eIF4F complex eIF4E 4EBP1 AKT mTORC1 mTORC2

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　　Cap-dependent translation is a potential cancer-related target (oncotarget) due to its critical role in cancer initiation and progression.

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The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK22

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