【摘 要】
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Microscopy has become a truly enabling visualization technique in biological and biomedical sciences.Nonlinear optical (NLO) microscopy has gained much attention owing to its intrinsic 3D resolution c
【机 构】
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Laboratory of Organic NanoPhotonics and Key Laboratory of Functional Crystals and Laser Technology,T
【出 处】
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中国微米纳米技术学会纳米科学技术分会第三届年会暨2014全国纳米生物与医学学术会议
论文部分内容阅读
Microscopy has become a truly enabling visualization technique in biological and biomedical sciences.Nonlinear optical (NLO) microscopy has gained much attention owing to its intrinsic 3D resolution capability,less photodamage and increased penetration depth.Typically,NLO microscopy techniques are referred to two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG) microscopy1,2.Probes are powerful tools for investigating molecular behavior in living tissues and cells.A variety of probes has been developed for staining subcellular structures,such as the cell membrane,mitochondria and DNA in the nucleus.
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