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Background Atherosclerosis remains the commonest cause of death in the world.Early detection of vulnerable plaque and quantitative detection of the disease are reliable bases for the clinical treatment.In our study, we assessed the correlations between plaque characteristics (including fibrous cap thickness, plaque components and plaque burden) and inflammatory activity by combined use of two non-invasive imaging methods-positron emission tomography/computed tomography (PET/CT) and magnetic resonance imaging (MRI).