【摘 要】
：
Self-assembled core/shell nanoparticles (NPs) were synthesized from water-soluble alginate substituted by hydrophobic phytosterols.Folate,a cancer-cell-specific ligand,was conjugated to the phytostero
【机 构】
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Department of Biochemistry and Molecular Biology,Anhui Province Key Laboratory of Biological Macro-m
【出 处】
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中国微米纳米技术学会纳米科学技术分会第三届年会暨2014全国纳米生物与医学学术会议
论文部分内容阅读
Self-assembled core/shell nanoparticles (NPs) were synthesized from water-soluble alginate substituted by hydrophobic phytosterols.Folate,a cancer-cell-specific ligand,was conjugated to the phytosterol-alginate (PA) NPs for targeting folate-receptor-expressing cancer cells.The physicochemical properties of folate-phytosterol-alginate (FPA) NPs were characterized by nuclear magnetic resonance,transmission electron microscopy,dynamic light scattering,and fluorescence spectroscopy.
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