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  5. The Oncolytic Effects of Bluetongue Virus(BTV) to Various Cell lines and Tumor

The Oncolytic Effects of Bluetongue Virus(BTV) to Various Cell lines and Tumor

来源 :2013第六届世界癌症大会 | 被引量 : 0次 | 上传用户：flyinsky_zxt
【摘 要】
：
High efficiency, specific targeting, and low-toxic treatments are now in great demand for cancer therapy.In this study, comparative analysis of differential cytopathic effects(CPEs), ultra-structural
【作 者】
：
Jun Hu Changyuan Dong Dong-E Chen Xingsan Tang 
【机 构】
：
Sun Yat-sen University China
【出 处】
：
2013第六届世界癌症大会
【发表日期】
：
2013年12期
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　　High efficiency, specific targeting, and low-toxic treatments are now in great demand for cancer therapy.In this study, comparative analysis of differential cytopathic effects(CPEs), ultra-structural changes, viral replication and genome transcription were carried out in cancer cell lines, continuous cells(NIH3T3) and primary murine embryo fibroblast (MEF) to test BTV-16s oncolytic ability in vitro.S 180 mice tumor model was used to determine the oncogenicity potential of BTV in vivo.
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