Effect of icraiin on memory of ordinarily aged rats

来源 :第十四届中国神经精神药理学学术会议 | 被引量 : 0次 | 上传用户:xy_zhuo
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  OBJECTIVE To investigate the effect of icariin on the memory of ordinarily aged male rats.METHODS 20 months old ordinarily male rats were intragastric administered icariin 30, 60, and 120 mg·kg-1 for 60 d, and normal negative control group was given equal-volume saline water, respectively.After the last administration, the memory ability of the rats is analysised by spatial behavior testing with the Morris water maze.All the animals were then anesthetized and decapitated to detect the vitalities of SOD, GSH-Px, Na + K +-ATPase and the amount of MDA in hippocampus.
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