【摘 要】
：
Gap junction channels mediate communication between adjacent cells by allowing the passage of a variety of cytoplasmic molecules.They are formed by the head to
【机 构】
：
ShanghaiInstituteforAdvancedImmunochemicalStudies,ShanghaiTechUniversityDepartmentofPhysicsandAstron
论文部分内容阅读
Gap junction channels mediate communication between adjacent cells by allowing the passage of a variety of cytoplasmic molecules.They are formed by the head to head docking of two connexin protein hexamers, known as hemichannels or connexons, located in two adjacent cells.
其他文献
IP3 receptor/PKC system is essential signaling systeminside the cell among which IP3 receptor (IP3R) system is directly linked to the Ca2+ signaling.Since IP3R
Isoform 3 of the plasma membrane calcium ATPase (PMCA3 pump), which is highly expressed in brain and cerebellum, plays an important role in the regulation of ne
The structure of theplasma membrane Ca2+ATPases (PMCA pumps) consists of 10 transmembranedomains, two large cytosolicloops, one of whichcontains the catalytic c
The plasma membrane calcium +ATPase (PMCApump) is a calcium transporting protein in the plasma membrane of cells.Its role is the regulation of the homeostasis o
Piwi-protein and piRNA pathway is mainly in the germline of a variety of species and exerts diverse functions including epigenetic regulation, transposon silenc
Short-lived conformational states in proteins are fundamental to protein function, but tend to be difficult to detect due to their transient nature such as intr
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signaling and trafficking.Its kinase activity criti
The current (from February 2014) Ebola virus disease (EVD) outbreak in West Africa is the largest one, and spread at an alarming rate, the mortality rate is abo
About 400 human olfactory receptors (ORs) can discriminate ＞1trillion olfactory stimuli.However,how they make the impossible to happen remains elusive.In fact, m
As the most important transmembrane signaling modulator, G protein-coupled receptors (GPCRs) are the most valuable therapeutic targets while GPCR-targeting drug