New cyclized 9,11-secosterols enol-ether from soft coral Pseudopterogorgia americana

来源 :中国化学会第十届全国天然有机化学学术会议 | 被引量 : 0次 | 上传用户:gracestoney
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Chemical investigation on the non-polar fraction of the MeOH extract from soft corel Pseudopteroagorgia americana afforded two rare sterols, americgorgosterol (1) and 3-acetyl-americgorgosterol (2), both containing an unusual seven-membered cyclic enol-ether in ring C and a cyclopropyl ring in the side chain, and a new 9,11-secosterol, 24-methylene-secogorgosterol (3),along with three related known analogues.Americgorgosterol (1) and 24-methylene-secogorgosterol (3) were converted to semi-synthetic sterols 4-6 and 7, respectively.
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