PALMITATE-INDUCED A BIPHASIC CELL DEATH IS RELATED TO ENDOPLASMIC RETICULUM STRESS AND DOWN-REGULATI

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：kayeyoo

【摘要】

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【作者】

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Yin Xia Cai Lu

【机构】

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The First Hospital of Jilin University,Changchun 130021,China;The First Hospital of Jilin University

【出处】

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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

：

2013年2期

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Objectives Cell death induced by lipid accumulation in the heart may contribute to cardiac complication of obesity and type 2 diabetes, but its mechnisms remain elusidative.Methods In the present study, we used H9c2 cardiac cell line and metallothione trasgene H9c2 cell line and treated the cells in vitro with palmitate at 62.5nM for 3 to 15 hours.

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PALMITATE-INDUCED A BIPHASIC CELL DEATH IS RELATED TO ENDOPLASMIC RETICULUM STRESS AND DOWN-REGULATI

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