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  5. Understanding and generating Foxp3+ regulatory T cells in vivo

Understanding and generating Foxp3+ regulatory T cells in vivo

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：luoshuinan
【摘 要】
：
CD4+CD25+Foxp3+ regulatory T cells (Tregs) are instrumental in the induction and maintenance of immune tolerance and in the prevention and therapy of chronic inflammation and autoimmunity.We previousl
【作 者】
：
Wanjun Chen 
【机 构】
：
Mucosal Immunology Section, OPCB, NIDCR, NIH,Bethesda, MD 20892, USA
【出 处】
：
中国免疫学会第九届全国免疫学学术大会
【发表日期】
：
2014年8期
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CD4+CD25+Foxp3+ regulatory T cells (Tregs) are instrumental in the induction and maintenance of immune tolerance and in the prevention and therapy of chronic inflammation and autoimmunity.We previously discovered that TGFβ induces Foxp3 in peripheral na(i)ve CD4+CD25-T cells and converts them into Foxp3+ regulatory T cells (iTregs)1.
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