Diagnostic accuracy of cardiovascular magnetic resonance for pulmonary hypertension A systematic rev

来源 :首都医科大学公共卫生学院第五届学术年会 | 被引量 : 0次 | 上传用户:liyan2006
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  Objective Conduct a systematic review and quantitative meta-analysis of literature, to determine the diagnostic accuracy of cardiovascular magnetic resonance for pulmonary hypertension.Methods Published literature was obtained by PUBMED;Web of Knowledge;Cochrane library;Embase;Biosis Preview;CNKI and Chongqing VIP databases and all studies were inclusive until December 2012.Studies relevant to pulmonary hypertension and its imaging in Cardiovascular Magnetic Resonance and right heart catheterization were included if correlation (cofecfient) was elucidated clearly.QUADAS-2 score assessed the quality of studies.Sensitivity and specificity were pooled separately and compared with overall accuracy measures: diagnostic odds ratio and symmetric summary receiver operating characteristic.Results 16 studies passed the selection criteria for inclusion and thus were included in the systematic review.The pooled diagnostic accuracy of ventricular mass index for pulmonary hypertension was modest, showing a summary sensitivity and specificity of 84% (95% CI: 79% to 87%) and 82% (95% CI: 73% to 89%) respectively.The area under summary ROC was 0.9095 and summary positive likelihood ratio was 4.894, which indicated that VMI of CMR has a modest ability to distinguish PH patients from healthy subjects across functional and structural measures at the very least.VMI, curvature ratio, RVWT(right ventricular wall thickness), RVWT/LVPWT (the ratio of RVWT to left ventricular posterior wall thickness), PVR(Pulmonary Vascular Resistance) have a better correlation with mean pulmonary arterial pressure and have a better diagnostic accuracy for pulmonary hypertension.Conclusions CMR appears to play an important role in the diagnostic of PH.Future studies should concentrate on the diagnostic accuracy of CMR in patients for whom ultrasound is impossible or inconclusive.With the advent of modern scanners and reducing cost, we hope it becomes one of the choice methods for management of PH.
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