Systematic analysis of diabetes-and glucose metabolism-related proteins and its application to Alzhe

来源 :2013年第四届全国“跨学科蛋白质研究”学术讨论会 | 被引量 : 0次 | 上传用户：hace

【摘要】

：

【作者】

：

杨洁

【机构】

：

南京大学生命科学学院医药生物技术国家重点实验室,南京210093

【出处】

：

2013年第四届全国“跨学科蛋白质研究”学术讨论会

【发表日期】

：

2013年2期

【关键词】

：

codon biases protein-protein interaction network BAD complex bioinformatics

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Alzheimer disease has been defined as Type 3 Diabetes due to their shared metabolic profiles.As well as our previously research results of Alzheimers disease and othe neurodegenerative diseases, systematic analysis of diabetesand glucose metabolism-related proteins also provides help in the treatment of Alzheimers patients.

其他文献

Structural and functional comparison of human Tig3 and H-REV107

TIG3 and H-REV107 belong to the H-REV107-1ike family.They function as class Ⅱ tumor suppressors and Ca2+-independent phospholipase A1/2.Overexpression of TIG3 or H-REV107 protein can induce apoptosis

会议

Ionic protein-lipid interaction, what the charge can do?

Plasma member is an asymmetrical lipid bilayer environment and its inner-leaflet is enriched of anionic phospholipids.The negatively charged anionic phospholipids can ionically interact with positivel

会议

Cocrystal structure of glycyl-tRNA synthetase in complex with tRNAGly reveals multiple conformationa

Aminoacyl-tRNA synthetases (aaRSs) are an ancient type of enzyme family that specifically recognizes and charges tRNA molecules with their cognate amino acids in an ATP-dependent reaction for protein

会议

The folding of βB1-crystallin is chaperoned by its N-terminal extension

β/γ-crystallins are the major structural proteins in mammalian lens, while β-crystallins exist as homomers or heteromers containing 2~8 subunits.The unique long N-terminal extension of βB 1-crystallin

会议

A novel R54L mutation in αA-crystallin causing autosomal dominant congenital nuclear cataract in a C

Congenital cataract is the leading cause of childhood blindness worldwide and about half of the cases are caused by genetic alternations.In this study, we identified a three-generation Chinese family

会议

Molecular modeling of the Candida albicans Vps4 and a virtual screening study for novel inhibitors

Candida albicans is an opportunistic human pathogen.Emergence of drug resistant strains makes it necessary to develop new anti-Candida drugs.Vps4 is an AAA ATPase critical for the function of the ESCR

会议

The importance of the last strand at the C-terminus in βB2-crystallin stability and assembly

Congenital cataract is the leading cause of childhood blindness worldwide.Investigations of the effects of inherited mutations on protein structure and function not only help us to understand the mole

会议

Involvement of MAP4K3 in mTORC1 signaling by amino acids nutrient

The mTOR (mammalian target of rapamycin) signaling pathway plays a major role in cell growth and metabolism in eukaryotes.In metazoans, the mTOR kinase exists in at least two distinct complexes, mTORC

会议

Candida albicans Vps4 is essential for the hyphal growth and is inhibited by AAA ATPase inhibitor DB

Candida albicans is an opportunist human pathogen.Its invasion into human tissue depends on its hyphal growth.Research shows many external signals triggers the process.One of this is alkaline pH that

会议

Comprehensive characterization of the glycosylation of OPN using integrated mass spectrometry-based

Osteopontin (OPN) is a multifunctional phosphorylated glycoprotein and it is involved in a broad range of functions in both physiological and pathological processes.

会议

osteopontin (OPN)Glycosylationmass spectrometrybead-based lectin array

Systematic analysis of diabetes-and glucose metabolism-related proteins and its application to Alzhe

与本文相关的学术论文