Selection of High-value Cell Lines for Monoclonal Antibody Expression Using ClonePix FL

来源 :中国上海第七届国际新药发明科技年会 | 被引量 : 0次 | 上传用户:hunterfall_horse
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  The pharmaceutical and biotechnology sectors are under pressure to reduce time and costs for discovery and development of new therapeutic antibodies.This hunt for the right cell candidate is fundamental at both the discovery stage (finding antigen-specific clones from hybridoma fusions) and the cell line development stage (isolating the highest producers from transfections).ClonePix FL is widely used to rapidly find and isolate the best clones from large heterogeneous cell populations for use as therapeutic protein producing cells.The power of this technology lies in its ability to visualize and quantify antibodies secreted from thousands of clones directly in cell culture plates,and to select and isolate only the highest value candidates,thus bypassing the need for high throughput automation.The technology also dramatically increases throughput,shortens timescales and reduces workload.
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