【摘 要】
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Classic studies recognize two functionally segregated macroglial cell types in the central nervous system (CNS),namely astrocytes and oligodendrocytes.A third macroglial cell type including a unique p
【机 构】
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Department of Neurobiology, Third Military Medical University, Chongqing 400038
【出 处】
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中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
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Classic studies recognize two functionally segregated macroglial cell types in the central nervous system (CNS),namely astrocytes and oligodendrocytes.A third macroglial cell type including a unique population of glial cells has now been identified by its specific expression of the NG2 chondroitin sulphate proteoglycan (NG2 glia) and described as oligodendrocyte precursor cells (OPCs).This study was undertaken to determine when most of NG2 cells exhibit adult characteristics in the rat cerebral cortex and hippocampus and whether these populations are present from birth or appear later on.Newborn (P0),postnatal day 7 (P7),P14,P21,P35,adult and old (more than 16 months) Sprague-Dawley rats were used in this study.For each result at least 5 animals and 20 slices were used in five independent experiments.
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