Rituximab, gemcitabine, cisplatin, and dexamethasone for patients with refractory or relapsed aggres

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户:fazaizhaoyun
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  This study was conducted to evaluate the efficacy and safety of rituximab, gemcitabine, cisplatin, and dexamethasone(R-GDP) for the treatment of relapsed or refractory aggressive B-Cell non-Hodgkins lymphoma (NHL).The treatments (every21 d) consisted of rituximab [375 mg/m2, intravenous (i.v.)on day 1], gemcitabine (1,000 mg/m2, i.v.on days 1 and 8),dexamethasone (40 mg i.v.on days 1 to 4), and cisplatin(25 mg/m2 i.v.on days 1 to 3).The primary end-points were overall survival (OS) and progression-free survival (PFS).
其他文献
Objective: To detect the mRNA expression levels of Dicerl,Drosha, D GCR8, and Ago2 in patients with PGI-DLBCL and to determine their prognostic values.Methods: A total of 40 PGI-DLBCL patients and 30
会议
Objective: The effect of rituximab (R) on central nervous system (CNS) relapse incidence in DLBCL patients is unclear.Methods: We performed a meta-analysis to explore the risk factors and assess the a
会议
Objective: To evaluate autologous stem cell transplant (ASCT)using fluorescence in situ hybridization (FISH) based on the survival of standard and high-risk MM patients.Methods: Seventy-four patients
会议
Objective: To determine the clinical and cytogenetic characteristics of non-Hodgkins lymphoma (NHL) in Shanghai.Methods: A retrospective analysis was conducted on 516patients with NHL.The clinical dat
会议
Objective: To evaluate the safety and efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) following a reduced-intensity conditioning (RIC) regimen for the treatment of refractor
会议
Objective: To evaluate the response and survival rates of refractory or relapsed Hodgkins lyrnphoma (HL) patients treated with autologous peripheral blood stem cell transplantation(APBSCT).Methods: Th
会议
Objective: To investigate the differential expression of TUBB gene in myelodysplastic syndrome (MDS) patients with and without leukemic evolution and to investigate the effects of the down-regulation
会议
Objective: To investigate the effects of ATG3 gene overexpression by lentivirus on SKM-1 cell line and of the ATG3gene on myelodysplastic syndrome to leukemic transformation.Methods: The lentivirus ve
会议
Objective: B-cell activation factor (BAFF) and BAFF-receptor(BAFF-R) play crucial roles in the survival and proliferation of malignant B-cells.Limited information exists on the expression profiles and
会议
Follicular lymphoma (FL) is a common indolent or low-grade non-Hodgkins lymphoma (NHL).Histologic transformation to high-grade lymphoma, which is generally diffuse large B-cell lymphoma (DLBCL), occur
会议