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异长春花碱(长春瑞宾,商品名诺维本,ＮＶＢ)由法国学者ＰｉｅｒｒｅＰｏｔｉｅｒ于1978年在法国ＣＮＲＳ(ＣｅｎｔｒｅＮａｔｉｏｎａｌｄｅＲｅｃｈｅｒｃｈｅＳｃｉｅｎｔｉｆｉｑｕｅ)合成。1989年由法国皮尔法伯制药公司生产上市后,ＮＶＢ很快显示出引人注目的抗肿瘤活性,?
Vincristine (Vinorelbine, NVB) was synthesized by the French scholar PierrePotier in 1978 at CNRS (Center National de Recherche Scientifique), France. NVB soon showed remarkable anti-tumor activity after it was launched in 1989 by the French company Pierfab.