目的:调查我院2008年上半年住院患者抗菌药应用情况,评价抗菌药应用合理性,为规范我院抗菌药管理提供依据。方法:随机抽取2008年1～6月出院病历3 123份,对抗菌药使用情况进行回顾性分析。结果:我院住院患者抗菌药使用率为60.58%,用药以单一用药为主(60.10%),二联用药占29.97%,三联用药占9.93%;按药敏试验用药率仅为28.64%。结论:我院住院患者的抗菌药应用率较高,用药前相关标本送检率较低,围手术期用药时机不当,预防性用药时间过长,应引起重视。 OBJECTIVE: To investigate the application of antibacterials in hospitalized patients in the first half of 2008 in our hospital to evaluate the rationality of antibacterials application and provide the basis for regulating the administration of antibacterials in our hospital. Methods: A total of 3 123 medical records were collected from January to June in 2008, and the use of antibacterials was retrospectively analyzed. Results: The use rate of antibacterials was 60.58% in hospitalized patients in our hospital. The single drug was used mainly (60.10%), the second drug was 29.97% and the triple drug was 9.93%. The drug use rate was only 28.64%. Conclusion: Inpatients in our hospital have a higher rate of antibacterial drug application, lower rate of pre-medication related samples, improper timing of perioperative medication, and prolonged preventive medication, which should be paid more attention to.