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目的了解IgG抗-D抗体与新生儿溶血病关系。方法采用盐水法检测患儿和其父母Rh血型,采用直接抗人球蛋白试验、游离抗体试验、放散试验检测ABO以外的抗体,采用微柱凝胶间接抗人球蛋白试验进行抗体鉴定。结果通过母婴血型血清学检查,检出IgG抗-D 7例。结论一旦证实有IgG抗-D,及时为新生儿溶血病患儿选择相合的血液进行换血和综合治疗,其疗效显著。
Objective To understand the relationship between IgG anti-D antibody and hemolytic disease of newborn. Methods The Rh blood type of children and their parents were detected by saline method. Antibody was detected by direct anti-human globulin test, free antibody test and disperse test. Antibody was identified by micro-column gel indirect anti-human globulin test. Results By maternal and child blood group serological tests, IgG anti-D 7 cases were detected. Conclusion Once confirmed with IgG anti-D, timely selection for children with hemolytic disease in children with hemophagocytic and comprehensive treatment, the effect is significant.