口腔干燥在处理方面有许多困难,放疗后的口腔干燥在治疗上就更困难了。因为放疗可以引起涎腺不可逆的损伤。有学者认为腺泡细胞对射线非常敏感,有的提出放疗的主要损伤部位不是腺泡细胞,而是腺体中的结缔组织。已有资料证明,Antholetrithione(ANTT)对药物性口腔干燥、Sjgren综合征和放疗以后的口干是有益的,毛果芸香碱对放射性口腔干燥有一定治疗作用。作者通过临床试验证明两种催涎药的合用对放疗所致的口腔干燥效果较好。资料和方法由头颈部癌接受放疗后的随 Dry mouth has many difficulties in handling. Drying after radiotherapy is more difficult to treat. Because radiotherapy can cause irreversible damage to the parotid gland. Some scholars believe that acinar cells are very sensitive to radiation, and some suggest that the main site of injury in radiotherapy is not acinar cells, but connective tissue in the gland. It has been proven that Antholetrithione (ANTT) is beneficial to dry mouth after drug-induced dry mouth, Sjgren syndrome, and radiotherapy. Pilocarpine has a certain therapeutic effect on radioactive dry mouth. The authors have demonstrated through clinical trials that the combination of two kinds of reminder drugs has a good effect on oral dryness caused by radiotherapy. Data and Methods Followed by Radiotherapy for Head and Neck Cancers