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【目的】探讨腔内治疗合并糖尿病的周围动脉闭塞性病变(Peripheral Arterial Occlusive Disease , PAOD)的疗效。【方法】回顾性分析35例伴发糖尿病的PAOD患者48次腔内治疗的临床资料。【结果】腔内操作技术成功率97.1%,术后30 d无死亡病例。术前踝肱指数(0.419±0.142)显著低于术后(0.741±0.158),其差异有统计学意义( P <0.01);6个月、12个月、24个月及36个月的初次通畅率分别为85.2%、61.9%、54.3%及46.2%,二次通畅率分别为91.5%、83.1%、70.2%及63.3%,肢体保存率分别为94.3%、88.6%、85.8%及82.9%。【结论】经皮腔内治疗糖尿病PAOD具有通畅率较高、并发症少的优点,能较好地保持患肢的完整性。“,”[Objective]To explore the efficacy of endoluminal therapy for diabetes mellitus with peripheral arterial occlusive disease(PAOD) .[Methods]Clinical data of 35 PAOD patients with diabetes mellitus treated by endoluminal therapy for 48 times were analyzed retrospectively .[Results] Endoluminal operation success rate was 97 .1% 34/35) .No one died 30d after operation .Ankle/brachial index before operation was (0 .419 ± 0 .142) which was markedly higher than that after operation (0 .741 ± 0 .158) ,and there was significant difference( P < 0 .001) .Primary patency rate at 6 months ,12 months ,24 months and 36 months was 85 .2% ,61 .9% ,54 .3% ,and 46 .2% respectively ,and .secondary patency rate was 91 .5% ,83 .1% ,70 .2%and 63 .3% respectively ,and limb preservation rate was 94 .3% ,88 .6% ,85 .8% and 82 .9% ,respectively .[Conclusion] Percutaneous endoluminal therapy for diabetic patients with PAOD has advantages such high pa-tency and few complications ,and can better remain the integrity of the affected limbs .