肿瘤作为一个复杂的组织,其中的肿瘤干细胞在肿瘤的生长、转移和复发过程中发挥至关重要的作用,因此靶向肿瘤干细胞治疗为肿瘤治愈提供了新的思路.新兴的纳米技术为克服传统药物的局限、有效靶向与杀伤肿瘤干细胞创造了可能.本文概述了肿瘤干细胞的特点,总结了目前靶向肿瘤干细胞的药物研究进展,并对靶向肿瘤干细胞纳米技术的应用进行了总结与展望. Tumor as a complex tissue in which cancer stem cells play a crucial role in the process of tumor growth, metastasis and recurrence.Therefore, targeting cancer stem cell therapy provides a new idea for the cure of tumors.The emerging nanotechnology is to overcome the traditional The limitations of drugs and the effective targeting and killing of cancer stem cells.This paper outlines the features of cancer stem cells and summarizes the current research progress of drugs that target cancer stem cells and summarizes the prospects of application of cancer stem cell nanotechnology .