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本文报告氟康唑和酮康唑胶囊治疗念珠菌性阴道炎的临床效果。氟康唑组和酮康唑组各２５例。每天服药２次，每次服１粒胶囊，共５天。氟康唑总剂量为１５０ｍｇ，酮康唑总剂量为２０００ｍｇ。治疗结果表明，两组的治愈率和真菌阴转率基本相同，两种药物均有效。对５０株念珠菌作了体外抗菌活性试验，发现氟康唑的ＭＩＣ相对偏高，酮康唑的ＭＩＣ相对偏低，说明酮康唑对白念珠菌、克柔氏念珠菌、假热带念珠菌的抑菌活性强于氟康唑。据文献报告，在动物体内试验抗白念珠菌活性氟康唑又强于酮康唑。
This article reports the clinical efficacy of fluconazole and ketoconazole capsules in the treatment of candidal vaginitis. Fluconazole group and ketoconazole group 25 cases. Take 2 times a day, take 1 capsule each time, a total of 5 days. The total fluconazole dose was 150 mg and the total ketoconazole dose was 2000 mg. Treatment results show that the two groups of cure rates and fungus negative conversion rate is basically the same, the two drugs are effective. 50 strains of Candida in vitro antibacterial activity test found that fluconazole MIC relatively high ketoconazole MIC relatively low, indicating that Ketoconazole Candida albicans, Candida krusei, Candida tropicalis Candida Antibacterial activity than fluconazole. According to the literature report, tests of anti-Candida albicans activity in animals in vivo fluconazole is stronger than that of ketoconazole.