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B因子为C3激活剂前体,是补体旁路活化途径中的一个重要因子,主要由肝脏和巨噬细胞合成。它是参与补体旁路活化的重要成分,参与机体防御,在组织和细胞损伤和炎症过程中均起重要作用。已有研究报道[1]血清中的B因子含量测定对良恶性肿瘤的鉴别有参考价值。本研究利用免疫透射比浊法检测426例正常人及186例肿瘤患者血清B因子的含量,探讨血清B因子在肿瘤诊断及预后中的临床应用价值。现将研究结果报告如下。
Factor B is a C3 activator precursor and is an important factor in complement pathway activation and is synthesized mainly by the liver and macrophages. It is involved in complement activation by bypassing an important component involved in body defense and plays an important role in tissue and cell damage and inflammation. It has been reported [1] serum B factor in the determination of benign and malignant tumors have reference value. In this study, immunoturbidimetry was used to detect serum B-factor levels in 426 normal subjects and 186 cancer patients, and to explore the clinical value of serum factor B in the diagnosis and prognosis of tumors. The research results are reported below.